Exosomes for angiogenesis induction in ischemic disorders

K Moeinabadi‐Bidgoli, M Rezaee… - Journal of cellular …, 2023 - Wiley Online Library
Ischaemic disorders are leading causes of morbidity and mortality worldwide. While the
current therapeutic approaches have improved life expectancy and quality of life, they are …

Advances in the application of extracellular vesicles derived from three-dimensional culture of stem cells

W Chen, P Wu, C Jin, Y Chen, C Li, H Qian - Journal of …, 2024 - Springer
Stem cells (SCs) have been used therapeutically for decades, yet their applications are
limited by factors such as the risk of immune rejection and potential tumorigenicity …

IFPA Joan Hunt Senior Award in Placentology lecture: Extracellular vesicle signalling and pregnancy

GE Rice, C Salomon - Placenta, 2024 - Elsevier
The field of extracellular vesicle (EV) signalling has the potential to transform our
understanding of maternal-fetal communication and affords new opportunities for non …

Extracellular vesicles as human therapeutics: A scoping review of the literature

C Fusco, G De Rosa, I Spatocco… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are released by all cells and contribute to cell‐to‐cell
communication. The capacity of EVs to target specific cells and to efficiently deliver a …

Prospect of Mesenchymal Stem-Cell-Conditioned Medium in the Treatment of Acute Pancreatitis: A Systematic Review

K Pang, F Kong, D Wu - Biomedicines, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) have demonstrated potential in both clinical and pre-
clinical research for mitigating tissue damage and inflammation associated with acute …

Unlocking the potential of exosomes in cancer research: A paradigm shift in diagnosis, treatment, and prevention

S Khoushab, MH Aghmiuni, N Esfandiari… - … -Research and Practice, 2024 - Elsevier
Exosomes, which are tiny particles released by cells, have the ability to transport various
molecules, including proteins, lipids, and genetic material containing non-coding RNAs …

[HTML][HTML] Could extracellular vesicles derived from mesenchymal stem cells be a potential therapy for acute pancreatitis-induced cardiac injury?

LF Pan, ZQ Niu, S Ren, HH Pei, YX Gao… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) often leads to a high incidence of cardiac injury, posing significant
challenges in the treatment of severe AP and contributing to increased mortality rates …

A comprehensive review of engineered exosomes from preparation strategy to therapy applications

X Fan, Y Zhang, W Liu, M Shao, Y Gong, T Wang… - Biomaterials …, 2024 - pubs.rsc.org
Exosomes exhibit high bioavailability, biological stability, targeted specificity, low toxicity,
and low immunogenicity in shuttling various bioactive molecules such as proteins, lipids …

Bioengineering extracellular vesicle cargo for optimal therapeutic efficiency

CA René, RJ Parks - Molecular Therapy Methods & Clinical Development, 2024 - cell.com
Extracellular vesicles (EVs) have the innate ability to carry proteins, lipids, and nucleic acids
between cells, and thus these vesicles have gained much attention as potential therapeutic …

Microglial uptake of hADSCs-Exo mitigates neuroinflammation in ICH

L Zhao, J Li - Cellular Signalling, 2024 - Elsevier
Intracerebral hemorrhage (ICH) is associated with secondary neuroinflammation, leading to
severe central nervous system damage. Exosomes derived from human adipose-derived …