Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

Epidemiological sex differences in anxiety disorders and major depression are well
characterized. Yet the circuits and mechanisms that contribute to these differences are …

Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …

The mechanisms underlying the pathophysiology and treatment of depression and stress-
related disorders remain unclear, but studies in depressed patients and rodent models are …

Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Depression is a common mental illness, affecting more than 300 million people worldwide.
Decades of investigation have yielded symptomatic therapies for this disabling condition but …

Despite extensive study of the neurobiological correlates of post-traumatic stress disorder
(PTSD), little is known about its molecular determinants. Here, differential gene expression …

Prevalence, symptoms, and treatment of depression suggest that major depressive
disorders (MDD) present sex differences. Social stress-induced neurovascular pathology is …

Observations of the disproportionate incidence of depression in women compared with men
have long preceded the recent explosion of interest in sex differences. Nonetheless, the …