Cellular infiltration in traumatic brain injury
Traumatic brain injury leads to cellular damage which in turn results in the rapid release of
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
damage-associated molecular patterns (DAMPs) that prompt resident cells to release …
Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury
M Hanscom, DJ Loane… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …
an understanding of both the primary neurological injury and the secondary sequelae that …
Innate immune responses to trauma
M Huber-Lang, JD Lambris, PA Ward - Nature immunology, 2018 - nature.com
Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …
Coagulopathy and haemorrhagic progression in traumatic brain injury: advances in mechanisms, diagnosis, and management
M Maegele, H Schöchl, T Menovsky… - The Lancet …, 2017 - thelancet.com
Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …
Sepsis-associated encephalopathy: a vicious cycle of immunosuppression
C Ren, R Yao, H Zhang, Y Feng, Y Yao - Journal of neuroinflammation, 2020 - Springer
Sepsis-associated encephalopathy (SAE) is commonly complicated by septic conditions,
and is responsible for increased mortality and poor outcomes in septic patients …
and is responsible for increased mortality and poor outcomes in septic patients …
Neuroinflammation in animal models of traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity worldwide.
Neuroinflammation is prominent in the short and long-term consequences of neuronal …
Neuroinflammation is prominent in the short and long-term consequences of neuronal …
Emerging roles for the immune system in traumatic brain injury
Traumatic brain injury (TBI) affects an ever-growing population of all ages with long-term
consequences on health and cognition. Many of the issues that TBI patients face are thought …
consequences on health and cognition. Many of the issues that TBI patients face are thought …
The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments
MC Morganti-Kossmann, BD Semple, SC Hellewell… - Acta …, 2019 - Springer
This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …
of neuroinflammation in the injured brain following trauma. We summarise the literature …
Beyond the brain: peripheral interactions after traumatic brain injury
Traumatic brain injury (TBI) is a leading cause of death and disability, and there are currently
no pharmacological treatments known to improve patient outcomes. Unquestionably …
no pharmacological treatments known to improve patient outcomes. Unquestionably …
Multiple organ dysfunction after trauma
Background The nature of multiple organ dysfunction syndrome (MODS) after traumatic
injury is evolving as resuscitation practices advance and more patients survive their injuries …
injury is evolving as resuscitation practices advance and more patients survive their injuries …