Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases

LA Adams, QM Anstee, H Tilg, G Targher - Gut, 2017 - gut.bmj.com
Key physiological functions of the liver, including glucose and lipid metabolism, become
disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated …

Hypertension, diabetes, atherosclerosis and NASH: cause or consequence?

A Lonardo, F Nascimbeni, A Mantovani, G Targher - Journal of hepatology, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has become one of the most common forms of
chronic liver disease worldwide and its prevalence is expected to continue rising. NAFLD …

[HTML][HTML] NAFLD: a multisystem disease

CD Byrne, G Targher - Journal of hepatology, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in Western countries that is predicted to become also the most frequent indication for liver …

Nonalcoholic Fatty Liver Disease and the Heart: JACC State-of-the-Art Review

EP Stahl, DS Dhindsa, SK Lee, PB Sandesara… - Journal of the American …, 2019 - jacc.org
Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD) are both
manifestations of end-organ damage of the metabolic syndrome. Through multiple …

Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications

SM Francque, D Van Der Graaff, WJ Kwanten - Journal of hepatology, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has become one of the most frequent chronic liver
diseases in the Western society and its prevalence is likely to rise even further. An …

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

QM Anstee, G Targher, CP Day - Nature reviews Gastroenterology & …, 2013 - nature.com
NAFLD is a spectrum of progressive liver disease that encompasses simple steatosis,
NASH, fibrosis and, ultimately, cirrhosis. NAFLD is recognized as the hepatic component of …

Risk of cardiomyopathy and cardiac arrhythmias in patients with nonalcoholic fatty liver disease

QM Anstee, A Mantovani, H Tilg… - … reviews Gastroenterology & …, 2018 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a common, progressive liver disease that affects
up to one-quarter of the adult population worldwide. The clinical and economic burden of …

AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions

A Lonardo, F Nascimbeni, G Targher… - Digestive and Liver …, 2017 - Elsevier
This review summarizes our current understanding of nonalcoholic fatty liver disease
(NAFLD), a multi-factorial systemic disease resulting from a complex interaction between a …

Risk of cardiovascular events in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis

L Alon, B Corica, V Raparelli, R Cangemi… - European Journal of …, 2022 - academic.oup.com
Aims Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent disease and has been
repeatedly associated with an increased risk of cardiovascular disease. However, the extent …

Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes

E Levelt, M Mahmod, SK Piechnik, R Ariga… - Diabetes, 2016 - Am Diabetes Assoc
Concentric left ventricular (LV) remodeling is associated with adverse cardiovascular events
and is frequently observed in patients with type 2 diabetes mellitus (T2DM). Despite this, the …