The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …
Temporal development of the infant gut microbiome
RE Moore, SD Townsend - Open biology, 2019 - royalsocietypublishing.org
The majority of organisms that inhabit the human body reside in the gut. Since babies are
born with an immature immune system, they depend on a highly synchronized microbial …
born with an immature immune system, they depend on a highly synchronized microbial …
Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis
Background Necrotizing enterocolitis (NEC) is a catastrophic disease of preterm infants, and
microbial dysbiosis has been implicated in its pathogenesis. Studies evaluating the …
microbial dysbiosis has been implicated in its pathogenesis. Studies evaluating the …
Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome
AJ Gasparrini, B Wang, X Sun, EA Kennedy… - Nature …, 2019 - nature.com
Hospitalized preterm infants receive frequent and often prolonged exposures to antibiotics
because they are vulnerable to infection. It is not known whether the short-term effects of …
because they are vulnerable to infection. It is not known whether the short-term effects of …
Clinical implications of preterm infant gut microbiome development
Perturbations to the infant gut microbiome during the first weeks to months of life affect
growth, development and health. In particular, assembly of an altered intestinal microbiota …
growth, development and health. In particular, assembly of an altered intestinal microbiota …
Probiotics, prebiotics and amelioration of diseases
YL Tsai, TL Lin, CJ Chang, TR Wu, WF Lai… - Journal of biomedical …, 2019 - Springer
Dysbiosis of gut microbiota is closely related to occurrence of many important chronic
inflammations-related diseases. So far the traditionally prescribed prebiotics and probiotics …
inflammations-related diseases. So far the traditionally prescribed prebiotics and probiotics …
The role of the microbiome in the developmental origins of health and disease
LT Stiemsma, KB Michels - Pediatrics, 2018 - publications.aap.org
Although the prominent role of the microbiome in human health has been established, the
early-life microbiome is now being recognized as a major influence on long-term human …
early-life microbiome is now being recognized as a major influence on long-term human …
Preterm birth and sustained inflammation: consequences for the neonate
A Humberg, I Fortmann, B Siller, MV Kopp… - Seminars in …, 2020 - Springer
Almost half of all preterm births are caused or triggered by an inflammatory process at the
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …
Probiotics in disease prevention and treatment
Few treatments for human diseases have received as much investigation in the past 20
years as probiotics. In 2017, English‐language meta‐analyses totaling 52 studies …
years as probiotics. In 2017, English‐language meta‐analyses totaling 52 studies …
Fecal filtrate transplantation protects against necrotizing enterocolitis
Necrotizing enterocolitis (NEC) is a life-threatening gastrointestinal disorder afflicting
preterm infants, which is currently unpreventable. Fecal microbiota transplantation (FMT) is a …
preterm infants, which is currently unpreventable. Fecal microbiota transplantation (FMT) is a …