Lutein and zeaxanthin and their roles in age-related macular degeneration—neurodegenerative disease

M Mrowicka, J Mrowicki, E Kucharska, I Majsterek - Nutrients, 2022 - mdpi.com
Lutein and zeaxanthin belong to the xanthophyll family of carotenoids, which are pigments
produced by plants. Structurally, they are very similar, differing only slightly in the …

A systematic review of carotenoids in the management of age-related macular degeneration

DW Lem, PG Davey, DL Gierhart, RB Rosen - Antioxidants, 2021 - mdpi.com
Age-related macular degeneration (AMD) remains a leading cause of modifiable vision loss
in older adults. Chronic oxidative injury and compromised antioxidant defenses represent …

Age-related macular degeneration: epidemiology and clinical aspects

TDL Keenan, CA Cukras, EY Chew - … : From Clinic to Genes and Back to …, 2021 - Springer
Age-related macular degeneration (AMD) is a degenerative disease of the human retina
affecting individuals over the age of 55 years. This heterogeneous condition arises from a …

Prevalence, risk, and genetic association of reticular pseudodrusen in age-related macular degeneration: age-related eye disease study 2 report 21

A Domalpally, E Agrón, JW Pak, TD Keenan… - Ophthalmology, 2019 - Elsevier
Purpose To determine the prevalence of reticular pseudodrusen (RPD) in eyes with age-
related macular degeneration (AMD), assess the role of RPD as an independent risk factor …

[HTML][HTML] Subretinal drusenoid deposits, age-related macular degeneration, and cardiovascular disease

RT Smith, TW Olsen, V Chong, J Kim… - Asia-Pacific Journal of …, 2024 - Elsevier
Decades of studies on age-related macular degeneration (AMD), cardiovascular disease
and stroke have not found consistent associations between AMD and systemic vascular …

[HTML][HTML] Genotype-and phenotype-based subgroups in geographic atrophy secondary to age-related macular degeneration: the EYE-RISK Consortium

M Biarnés, JM Colijn, J Sousa, LL Ferraro, M Garcia… - Ophthalmology …, 2020 - Elsevier
Purpose Geographic atrophy (GA) secondary to age-related macular degeneration is
considered a single entity. This study aimed to determine whether GA subgroups exist that …

Local oral and nasal microbiome diversity in age-related macular degeneration

J Rullo, PM Far, M Quinn, N Sharma, S Bae, I Irrcher… - Scientific reports, 2020 - nature.com
Age-related macular degeneration (AMD) is a chronic degenerative disease of the retina.
Recent reports have highlighted the potential role of mucosal surface microbes in the …

Associations of ARMS2 and CFH Gene Polymorphisms with Neovascular Age-Related Macular Degeneration

S Supanji, DF Romdhoniyyah, MB Sasongko… - Clinical …, 2021 - Taylor & Francis
Purpose This study aimed to determine the association of ARMS2 A69S, ARMS2
del443ins54, and CFH Y402H polymorphisms with neovascular age-related macular …

The ARMS2 A69S polymorphism is associated with delayed rod-mediated dark adaptation in eyes at risk for incident age-related macular degeneration

RF Mullins, G McGwin Jr, K Searcey, ME Clark… - Ophthalmology, 2019 - Elsevier
Purpose To examine the association between sequence variants in genetic risk factors for
age-related macular degeneration (AMD) and delayed rod-mediated dark adaptation …

Subretinal drusenoid deposits: An update

M Monge, A Araya, L Wu - Taiwan Journal of Ophthalmology, 2022 - journals.lww.com
A wide spectrum of phenotypic manifestations characterizes age-related macular
degeneration (AMD). Drusen is considered the hallmark of AMD and is located underneath …