Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health

O Babenko, I Kovalchuk, GAS Metz - Neuroscience & Biobehavioral …, 2015 - Elsevier
Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Fibromyalgia: a critical and comprehensive review

AT Borchers, ME Gershwin - Clinical reviews in allergy & immunology, 2015 - Springer
Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise
classification. It is often considered as part of the global overview of functional somatic …

Glucocorticoids and fetal programming part 2: mechanisms

VG Moisiadis, SG Matthews - Nature Reviews Endocrinology, 2014 - nature.com
The lifelong health of an individual is shaped during critical periods of development. The
fetus is particularly susceptible to internal and external stimuli, many of which can alter …

DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain

AK Smith, V Kilaru, T Klengel, KB Mercer… - American Journal of …, 2015 - Wiley Online Library
DNA methylation has become increasingly recognized in the etiology of psychiatric
disorders. Because brain tissue is not accessible in living humans, epigenetic studies are …

DNA methylation biomarkers: cancer and beyond

T Mikeska, JM Craig - Genes, 2014 - mdpi.com
Biomarkers are naturally-occurring characteristics by which a particular pathological process
or disease can be identified or monitored. They can reflect past environmental exposures …

Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings

L Smigielski, V Jagannath, W Rössler, S Walitza… - Molecular …, 2020 - nature.com
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …

Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder

EL Dempster, R Pidsley, LC Schalkwyk… - Human molecular …, 2011 - academic.oup.com
Studies of the major psychoses, schizophrenia (SZ) and bipolar disorder (BD), have
traditionally focused on genetic and environmental risk factors, although more recent work …

Epigenetic modifications in schizophrenia and related disorders: molecular scars of environmental exposures and source of phenotypic variability

J Richetto, U Meyer - Biological Psychiatry, 2021 - Elsevier
Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Epigenomic dysregulation in schizophrenia: in search of disease etiology and biomarkers

B Khavari, MJ Cairns - Cells, 2020 - mdpi.com
Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …

Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients

LF Wockner, EP Noble, BR Lawford… - Translational …, 2014 - nature.com
Recent studies suggest that genetic and environmental factors do not account for all the
schizophrenia risk, and epigenetics also has a role in disease susceptibility. DNA …