To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

Inflammatory pathways drive atherogenesis and link conventional risk factors to
atherosclerosis and its complications. One inflammatory mediator has come to the fore as a …

The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

Tumor necrosis factor–α (TNF-α) blockers are a popular therapeutic choice in a number of
inflammatory diseases. Thus far, five TNF-α blockers have been approved for clinical use …

Intestinal epithelial cells (IECs) not only have a critical function in the absorption of nutrients,
but also act as a physical barrier between our body and the outside world. Damage and …

Cytokines are powerful mediators which play a central role in both innate and adapted
immune responses. Aberrant productions of cytokines may lead to the onset of immune …

Expression of matrix metalloproteinase 9 (MMP9) is elevated in a variety of inflammatory
and oncology indications, including ulcerative colitis and colorectal cancer. MMP9 is a …

Objective To provide a systematic review of the literature regarding the efficacy of anti‐
inflammatory drugs in three major mental disorders [major depressive disorder (MDD) …

Inflammatory bowel disease (IBD) is a complex disorder associated with a dysregulated
immune response to environmental triggers in the genetically susceptible host. The …