Cranial placodes are focal regions of thickened ectoderm in the head of vertebrate embryos
that give rise to a wide variety of cell types, including elements of the paired sense organs …

Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …

We analyzed the spatiotemporal pattern of expression of 15 transcription factors (Six1, Six4,
Eya1, Sox3, Sox2, Pax6, Pax3, Pax2, Pax8, Dlx3, Msx1, FoxI1c, Tbx2, Tbx3, Xiro1) during …

All vertebrates have directional asymmetries in the organization of their internal organs. In
jawed vertebrates, development of asymmetry is controlled by a conserved molecular …

Ectodermal placodes comprise the adenohypophyseal, olfactory, lens, profundal, trigeminal,
otic, lateral line, and epibranchial placodes. The first part of this review presents a brief …

Since the pioneering work of the early 1900s, the lens has been used as a model system for
the study of tissue development in vertebrates. A number of embryological transplantation …

In recent years, the zebrafish has become a favourite model organism for biologists studying
developmental processes in vertebrates. Its rapid embryonic development, the transparency …

The recessive aphakia (ak) mouse mutant is characterized by bilateral microphthalmia due
to a failure of lens morphogenesis. We fine-mapped the ak locus to the interval between …

The mammalian anterior pituitary gland is a compound endocrine organ that regulates
reproductive development and fitness, growth, metabolic homeostasis, the response to …

The genetic lesion leading to facioscapulohumeral muscular dystrophy (FSHD) is a
dominant deletion at the 4q35 locus. The generally accepted disease model involves an …