Pharmacokinetics, metabolism, distribution and permeability of nanomedicine

S Ravindran, JK Suthar, R Rokade… - Current drug …, 2018 - ingentaconnect.com
Background: Medical application of nanotechnology is termed as Nanomedicine and is
widely used in healthcare industries. Nanotechnology has helped Physicians, Scientists and …

Research progress of herbal medicines on drug metabolizing enzymes: consideration based on toxicology

S Wang, W Li, J Yang, Z Yang, C Yang… - Current Drug …, 2020 - ingentaconnect.com
The clinical application of herbal medicines is increasing, but there is still a lack of
comprehensive safety data and in-depth research into mechanisms of action. The …

Identification of CYP3A7 for glyburide metabolism in human fetal livers

DL Shuster, LJ Risler, B Prasad, JC Calamia… - Biochemical …, 2014 - Elsevier
Glyburide is commonly prescribed for the treatment of gestational diabetes mellitus;
however, fetal exposure to glyburide is not well understood and may have short-and long …

Rapid, Validated UPLC‐MS/MS Method for Determination of Glibenclamide in Rat Plasma

MA Alam, FI Al-Jenoobi… - International Journal of …, 2018 - Wiley Online Library
Quick and specific bioanalytical methods are required for analyzing drugs in biological
samples. A simple, quick, sensitive, and specific UPLC‐MS/MS method was developed and …

Effect of berberine on in vitro metabolism of sulfonylureas: A herb–drug interactions study

A Singh, K Zhao, C Bell, AJ Shah - Rapid Communications in …, 2020 - Wiley Online Library
Rationale Patients with type 2 diabetes may co‐ingest herbal and prescription medicines to
control their blood sugar levels. Competitive binding of drug and herb may mutually affect …

Simultaneous determination of paeoniflorin from total glucosides of paeony in Sprague–Dawley rats and spontaneously hypertensive rats by high‐performance liquid …

S Xiong, Y Wang - Biomedical Chromatography, 2016 - Wiley Online Library
Paeoniflorin is a well‐known monoterpene glucoside in the herbal drug that exhibits a
number of biological activities. The pharmacokinetic characteristics of paeoniflorin from total …

[PDF][PDF] Significance of biotransformation in drug discovery and development

S Ravindran, S Basu, P Surve, G Lonsane… - J Biotechnol …, 2012 - researchgate.net
Biotransformation is a process by which organic compounds are transformed from one form
to another, aided by organisms such as bacteria, fungi and enzymes. Biotransformations are …

Is glyburide safe in pregnancy?

Z Kimber-Trojnar, B Marciniak… - Current …, 2014 - ingentaconnect.com
The clinical recognition and adequate treatment of women with hyperglycemia during
pregnancy is significant in order to reduce neonatal complications correlated with …

[HTML][HTML] Purification of nanoparticles by liquid chromatography for biomedical and engineering applications

JK Suthar, R Rokade, A Pratinidi, R Kambadkar… - American Journal of …, 2017 - scirp.org
Nanoparticles are extensively used for various applications in science, engineering and
medicine. Synthesis of nanoparticles with high purity is essential to utilize the same in …

Metabolite identification of seven active components of Huan‐Nao‐Yi‐Cong‐Fang in rat plasma using high‐performance liquid chromatography combined with hybrid …

M Wang, Y Lu, J Liu, H Li, Y Wei - Biomedical Chromatography, 2016 - Wiley Online Library
Abstract Huan‐Nao‐Yi‐Cong‐Fang (HNYCF) is a potential prescription in treating
Alzheimer's disease. Seven constituents [ferulic acid (FA), 2, 3, 5, 4′‐tetrahydroxystilbene …