The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …

Nociception is an important physiological process that detects harmful signals and results in
pain perception. In this review, we discuss important experimental evidence involving some …

Transient receptor potential (TRP) channels are a superfamily of non-selective cation
channels that act as polymodal sensors in many tissues throughout mammalian organisms …

Objectives Several studies have found that inappropriate workstations are associated with
musculoskeletal disorders. The present cross-sectional study aimed to identify the risk …

Background Although there is an assertion that weather conditions affect osteoarthritis (OA)
pain, the results from clinical studies remain inconsistent. This meta-analysis was performed …

It is a well-known hypothesis that weather can influence human health, including pain
sensation. The primary meteorological factors are atmospheric pressure, wind, humidity …

Transient receptor potential ankyrin 1 (TRPA1) is a membrane-bound ion channel found in
neurons, where it mediates nociception and neurogenic inflammation. Recently, we have …

Huoxuezhitong capsule (HXZT, activating blood circulation and relieving pain capsule), has
been applied for osteoarthritis since 1974. It consists of Angelica sinensis (Oliv.) Diels …

Ongoing, spontaneous pain is characteristic of inflammatory joint pain and reduces an
individual's quality of life. To understand the neural basis of inflammatory joint pain, we …

Based on clinical and preclinical evidence, Transient Receptor Potential (TRP) channels
have emerged as potential drug targets for the treatment of osteoarthritis, rheumatoid …