[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease
K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …
cation channels remarkably conserved through the animal kingdom. Mammals have only …
Regulation of pain and itch by TRP channels
Nociception is an important physiological process that detects harmful signals and results in
pain perception. In this review, we discuss important experimental evidence involving some …
pain perception. In this review, we discuss important experimental evidence involving some …
Involvement of neural transient receptor potential channels in peripheral inflammation
HA Silverman, A Chen, NL Kravatz… - Frontiers in …, 2020 - frontiersin.org
Transient receptor potential (TRP) channels are a superfamily of non-selective cation
channels that act as polymodal sensors in many tissues throughout mammalian organisms …
channels that act as polymodal sensors in many tissues throughout mammalian organisms …
Risk factors of non-specific neck pain and low back pain in computer-using office workers in China: a cross-sectional study
S Ye, Q Jing, C Wei, J Lu - BMJ open, 2017 - bmjopen.bmj.com
Objectives Several studies have found that inappropriate workstations are associated with
musculoskeletal disorders. The present cross-sectional study aimed to identify the risk …
musculoskeletal disorders. The present cross-sectional study aimed to identify the risk …
Associations between weather conditions and osteoarthritis pain: A systematic review and meta-analysis
L Wang, Q Xu, Y Chen, Z Zhu, Y Cao - Annals of Medicine, 2023 - Taylor & Francis
Background Although there is an assertion that weather conditions affect osteoarthritis (OA)
pain, the results from clinical studies remain inconsistent. This meta-analysis was performed …
pain, the results from clinical studies remain inconsistent. This meta-analysis was performed …
[HTML][HTML] Pain and weather associations–Action mechanisms; personalized profiling
G Horvath, K Nagy, G Tuboly, E Nagy - Brain Research Bulletin, 2023 - Elsevier
It is a well-known hypothesis that weather can influence human health, including pain
sensation. The primary meteorological factors are atmospheric pressure, wind, humidity …
sensation. The primary meteorological factors are atmospheric pressure, wind, humidity …
Transient receptor potential ankyrin 1 (TRPA1) is involved in upregulating interleukin-6 expression in osteoarthritic chondrocyte models
E Nummenmaa, M Hämäläinen, A Pemmari… - International Journal of …, 2020 - mdpi.com
Transient receptor potential ankyrin 1 (TRPA1) is a membrane-bound ion channel found in
neurons, where it mediates nociception and neurogenic inflammation. Recently, we have …
neurons, where it mediates nociception and neurogenic inflammation. Recently, we have …
[HTML][HTML] Huoxuezhitong capsule ameliorates MIA-induced osteoarthritis of rats through suppressing PI3K/Akt/NF-κB pathway
L Ju, P Hu, P Chen, X Xue, Z Li, F He, Z Qiu… - Biomedicine & …, 2020 - Elsevier
Huoxuezhitong capsule (HXZT, activating blood circulation and relieving pain capsule), has
been applied for osteoarthritis since 1974. It consists of Angelica sinensis (Oliv.) Diels …
been applied for osteoarthritis since 1974. It consists of Angelica sinensis (Oliv.) Diels …
[HTML][HTML] Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner
Ongoing, spontaneous pain is characteristic of inflammatory joint pain and reduces an
individual's quality of life. To understand the neural basis of inflammatory joint pain, we …
individual's quality of life. To understand the neural basis of inflammatory joint pain, we …
Evidence for transient receptor potential (TRP) channel contribution to arthritis pain and pathogenesis
T Galindo, J Reyna, A Weyer - Pharmaceuticals, 2018 - mdpi.com
Based on clinical and preclinical evidence, Transient Receptor Potential (TRP) channels
have emerged as potential drug targets for the treatment of osteoarthritis, rheumatoid …
have emerged as potential drug targets for the treatment of osteoarthritis, rheumatoid …