Uric acid is the final oxidation product of purine metabolism in humans. Xanthine
oxidoreductase (XOR) catalyzes oxidative hydroxylation of hypoxanthine to xanthine to uric …

This article aims to critically review the evidence on the available therapeutic strategies for
the treatment of hyperuricemia. For this reason, several papers were reviewed. Xanthine …

This review aims to critically present the available clinical evidence supporting the treatment
of chronic hyperuricemia with xanthine oxidase inhibitors. For this reason, the studies …

Pulmonary hypertension (PH) is a progressive lethal disease, which is characterized by
abnormal vascular remodeling and persistently elevated pulmonary artery pressure …

Several studies suggest that chronic hyperuricemia, the main precursor of gout, is involved
in the pathogenesis of different systemic disorders that affect cardiovascular and renal …

The abnormal metabolism of uric acid results in many disease such as chronic kidney
disease, hyperuricemia, nephrolithiasis, gout, hypertension, vascular disease and so on …

A simple dual-read assay for uric acid (UA) was developed based on a combined ratiometric
fluorescent and colorimetric strategy using nitrogen-doped carbon dots (N-CDs). The …

Borghi and Desideri Allopurinol and Cardiovascular Disease 497 the increase in the
endothelium-dependent forearm vasodilatation was enhanced by allopurinol in a dose …

Several epidemiological studies have demonstrated the existence of a correlation between
high serum uric acid (SUA) levels, hypertension, and chronic kidney disease (CKD). Xantine …

Background The association between uric acid (UA) and coronary artery disease (CAD) was
controversial. It was still unclear how the UA level changes with age and gender. Aims To …