Involvement of oxidative stress in the development of subcellular defects and heart disease
NS Dhalla, V Elimban, M Bartekova, A Adameova - Biomedicines, 2022 - mdpi.com
It is now well known that oxidative stress promotes lipid peroxidation, protein oxidation,
activation of proteases, fragmentation of DNA and alteration in gene expression for …
activation of proteases, fragmentation of DNA and alteration in gene expression for …
Monoamine oxidase‐related vascular oxidative stress in diseases associated with inflammatory burden
A Sturza, CM Popoiu, M Ionică… - Oxidative medicine …, 2019 - Wiley Online Library
Monoamine oxidases (MAO) with 2 isoforms, A and B, located at the outer mitochondrial
membrane are flavoenzyme membranes with a major role in the metabolism of …
membrane are flavoenzyme membranes with a major role in the metabolism of …
Histamine can be Formed and Degraded in the Human and Mouse Heart
J Neumann, JM Grobe, J Weisgut… - Frontiers in …, 2021 - frontiersin.org
Histamine is metabolized by several enzymes in vitro and in vivo. The relevance of this
metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive …
metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive …
Monoamine oxidases are novel sources of cardiovascular oxidative stress in experimental diabetes
A Sturza, OM Duicu, A Vaduva… - Canadian Journal of …, 2015 - cdnsciencepub.com
Diabetes mellitus (DM) is widely recognized as the most severe metabolic disease
associated with increased cardiovascular morbidity and mortality. The generation of reactive …
associated with increased cardiovascular morbidity and mortality. The generation of reactive …
Assessment of mitochondrial dysfunction and monoamine oxidase contribution to oxidative stress in human diabetic hearts
OM Duicu, R Lighezan, A Sturza… - Oxidative medicine …, 2016 - Wiley Online Library
Mitochondria‐related oxidative stress is a pathomechanism causally linked to coronary heart
disease (CHD) and diabetes mellitus (DM). Recently, mitochondrial monoamine oxidases …
disease (CHD) and diabetes mellitus (DM). Recently, mitochondrial monoamine oxidases …
Increased MAO-A activity promotes progression of pulmonary arterial hypertension
XQ Sun, EL Peters, I Schalij, JB Axelsen… - American journal of …, 2021 - atsjournals.org
Monoamine oxidases (MAOs), a class of enzymes bound to the outer mitochondrial
membrane, are important sources of reactive oxygen species. Increased MAO-A activity in …
membrane, are important sources of reactive oxygen species. Increased MAO-A activity in …
Ischemia–Reperfusion Injury: Molecular Mechanisms of Pathogenesis and Methods of Their Correction
RG Goncharov, MG Sharapov - Molecular Biology, 2023 - Springer
Ischemia–reperfusion is a cascade of complex and interrelated pathological processes
underlying many human diseases, including such socially significant diseases as stroke …
underlying many human diseases, including such socially significant diseases as stroke …
Effects of berberine on cholinesterases and monoamine oxidase activities, and antioxidant status in the brain of streptozotocin (STZ)-induced diabetic rats
SA Adefegha, FA Dada, SI Oyeleye… - Journal of Basic and …, 2022 - degruyter.com
Objectives Several studies had been conducted to examine the link between diabetes and
diabetes encephalopathy. This study was conducted to examine the potency of berberine …
diabetes encephalopathy. This study was conducted to examine the potency of berberine …
Monoamine oxidase inhibition improves vascular function in mammary arteries from nondiabetic and diabetic patients with coronary heart disease
R Lighezan, A Sturza, OM Duicu… - Canadian journal of …, 2016 - cdnsciencepub.com
Monoamine oxidases (MAOs) are mitochondrial enzymes with 2 isoforms that have emerged
as important contributors to cardiovascular oxidative stress via the constant generation of …
as important contributors to cardiovascular oxidative stress via the constant generation of …
Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts
OM Duicu, A Privistirescu, A Wolf… - Canadian Journal of …, 2017 - cdnsciencepub.com
Diabetic cardiomyopathy has been systematically associated with compromised
mitochondrial energetics and increased generation of reactive oxygen species (ROS) that …
mitochondrial energetics and increased generation of reactive oxygen species (ROS) that …