Druggable molecular targets for the treatment of triple negative breast cancer

M Nakhjavani, JE Hardingham… - Journal of breast …, 2019 - synapse.koreamed.org
Breast cancer (BC) is still the most common cancer among women worldwide. Amongst the
subtypes of BC, triple negative breast cancer (TNBC) is characterized by deficient …

Cancer therapy–related salivary dysfunction

C Paz, A Glassey, A Frick, S Sattar, NG Zaorsky… - The Journal of Clinical …, 2024 - jci.org
Salivary gland dysfunction is a common side effect of cancer treatments. Salivary function
plays key roles in critical daily activities. Consequently, changes in salivary function can …

Stereoselective anti-cancer activities of ginsenoside Rg3 on triple negative breast cancer cell models

M Nakhjavani, HM Palethorpe, Y Tomita, E Smith… - Pharmaceuticals, 2019 - mdpi.com
Ginsenoside Rg3 (Rg3) has two epimers, 20 (S)-ginsenoside Rg3 (SRg3) and 20 (R)-
ginsenoside Rg3 (RRg3), and while Rg3 itself has been reported to have anti-cancer …

Combined systematic review and transcriptomic analyses of mammalian aquaporin classes 1 to 10 as biomarkers and prognostic indicators in diverse cancers

PH Chow, J Bowen, AJ Yool - Cancers, 2020 - mdpi.com
Aquaporin (AQP) channels enable regulated transport of water and solutes essential for fluid
homeostasis, but they are gaining attention as targets for anticancer therapies. Patterns of …

Based on Histogram Analysis: ADCaqp Derived from Ultra-high b-Value DWI could be a Non-invasive Specific Biomarker for Rectal Cancer Prognosis

G Zhang, W Ma, H Dong, J Shu, W Hou, Y Guo… - Scientific Reports, 2020 - nature.com
Aquaporins (AQP) are not only water channel protein, but also potential prognostic indicator
and therapeutic target for rectal cancer. Some previous studies have demonstrated the AQP …

Skin biological responses to urban pollution in an ex vivo model

A Patatian, C Delestre-Delacour, G Percoco… - Toxicology letters, 2021 - Elsevier
The skin epidermis is continuously exposed to external aggressions, including
environmental pollution. The cosmetic industry must be able to offer dedicated products to …

High preoperative levels of circulating SFRP5 predict better prognosis in colorectal cancer patients

C Kirana, E Smith, DT Ngo, MI Trochsler… - Future …, 2020 - Taylor & Francis
The purpose of this research was to investigate the diagnostic and prognostic value of
circulating SFRP5 (cSFRP5) in colorectal cancer (CRC). We evaluated preoperative …

Integrative Analysis Reveals Comprehensive Altered Metabolic Genes Linking with Tumor Epigenetics Modification in Pan‐Cancer

Y Shi, J Wei, Z Chen, Y Yuan, X Li… - BioMed research …, 2019 - Wiley Online Library
Background. Cancer cells undergo various rewiring of metabolism and dysfunction of
epigenetic modification to support their biosynthetic needs. Although the major features of …

Aquaporins in colorectal cancer: exploring their role in tumorigenesis, metastasis, and drug response

M Azimi Mohammadabadi, A Moazzeni, L Jafarzadeh… - Human Cell, 2024 - Springer
Aquaporins (AQPs) are small, integral proteins facilitating water transport across plasma cell
membranes in response to osmotic gradients. This family has 13 unique members (AQP0 …

[HTML][HTML] DNA甲基化调控牛AQP1基因的胎盘特异性印记

刘晓倩, 靳兰杰, 董艳秋, 李冬杰, 张萃, 谷书凯… - 畜牧兽医学报, 2021 - xml-data.org
为揭示牛AQP1 (aquaporin 1) 基因在不同组织及胎盘中的印记状态, 以及DNA
甲基化修饰在印记中的调控机制, 本研究采用基于SNP 的PCR 产物直接测序的方法, 对32 …