Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

Recent years have seen several advances in our understanding of immunity to virus
infection of the lower respiratory tract, including to influenza virus infection. Here, we review …

Human respiratory syncytial virus (RSV) was first isolated in 1956 from a laboratory
chimpanzee with upper respiratory tract disease (for general reviews, see references 21, 57 …

Immune tolerance is instituted early in life, during which time regulatory T (Treg) cells have
an important role. Recurrent infections with respiratory syncytial virus (RSV) in early life …

Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract
disease, especially in young children. Despite its global impact on healthcare, related to its …

Severe respiratory syncytial virus (RSV) infections are characterized by airway epithelial cell
damage, mucus hypersecretion, and Th2 cytokine production. Less is known about the role …

BACKGROUND: Respiratory viral infection, including respiratory syncytial virus (RSV) and
rhinovirus, has been linked to respiratory disease in pediatric patients, including severe …

Infection with the human pneumovirus pathogen, respiratory syncytial virus (hRSV), causes
a wide spectrum of respiratory disease, notably among infants and the elderly. Laboratory …

The resolution of infection is an active process with specific molecular and cellular
mechanisms that temper inflammation and enhance pathogen clearance. Here, the …

Airway mucus is a hallmark of respiratory syncytial virus (RSV) lower respiratory tract illness.
Laboratory RSV strains differentially induce airway mucus production in mice. Here, we …