Alzheimer's disease (AD) is a neurodegenerative disorder characterized by decreased
synaptic transmission and cerebral atrophy with appearance of amyloid plaques and …

Alzheimer's disease (AD) is a chronic and irreversible neurodegenerative disorder with
progressive dementia and cognitive impairment. AD poses severe health challenge in …

In the present study, a series of fascinating chalcone derivatives 1C-14C has been designed
and synthesized by Claisen-Schmidt condensation. The target compounds were screened …

Abstract Eleven piperazine-containing 1, 3-diphenylprop-2-en-1-one derivatives (PC1-
PC11) were evaluated for their inhibitory activities against monoamine oxidases (MAOs) …

Six halogenated trimethoxy chalcone derivatives (CH1–CH6) were synthesized and
spectrally characterized. The compounds were further evaluated for their inhibitory potential …

Alzheimer's disease (AD) is the most common form of dementia among the elderly,
accounting for 60% to 70% of cases. At present, the pathogenesis of this condition remains …

Alzheimer's disease (AD) is a progressive brain disease characterised by progressive
memory loss and cognition impairment, ultimately leading to death. There are three FDA …

Monoamine oxidase-B (MAO-B), acetylcholinesterase (AChE), and butyrylcholinesterase
(BChE) have been considered target enzymes of depression and neurodegenerative …

Along with the increase in life expectancy, a significant increase of people suffering from
neurodegenerative diseases (ND) has been noticed. The second most common ND, after …

A series of novel benzimidazole-derived carbohydrazones was designed, synthesized and
evaluated for their dual inhibition potential against monoamine oxidases (MAOs) and …