Long COVID-19 pathophysiology: what do we know so far?

NR Tziolos, P Ioannou, S Baliou, DP Kofteridis - Microorganisms, 2023 - mdpi.com
Long COVID-19 is a recognized entity that affects millions of people worldwide. Its broad
clinical symptoms include thrombotic events, brain fog, myocarditis, shortness of breath …

Autoimmune complications of COVID-19 and potential consequences for long-lasting disease syndromes

J Amiral, J Seghatchian - Transfusion and Apheresis Science, 2023 - Elsevier
The latest WHO report determined the increasing diversity within the CoV-2 omicron and its
descendent lineages. Some heavily mutated offshoots of BA. 5 and BA. 2, such as BA. 4.6 …

Microbiome profiling using shotgun metagenomic sequencing identified unique microorganisms in COVID-19 patients with altered gut microbiota

S Li, S Yang, Y Zhou, C Disoma, Z Dong, A Du… - Frontiers in …, 2021 - frontiersin.org
COVID-19 is mainly associated with respiratory distress syndrome, but a subset of patients
often present gastrointestinal (GI) symptoms. Imbalances of gut microbiota have been …

[HTML][HTML] Coronavirus disease 2019 and the gut–lung axis

D Zhou, Q Wang, H Liu - International Journal of Infectious Diseases, 2021 - Elsevier
Gastrointestinal and respiratory tract diseases often occur together. There are many
overlapping pathologies, leading to the concept of the 'gut–lung axis' in which stimulation on …

Angiotensin-(1-7)—a potential remedy for AKI: insights derived from the COVID-19 pandemic

SN Heyman, T Walther, Z Abassi - Journal of Clinical Medicine, 2021 - mdpi.com
Membrane-bound angiotensin converting enzyme (ACE) 2 serves as a receptor for the Sars-
CoV-2 spike protein, permitting viral attachment to target host cells. The COVID-19 …

[HTML][HTML] Effects of different routes and forms of vitamin D administration on CD4+ T cell homeostasis and renin-angiotensin system-associated lung injury in obese …

CL Yeh, JM Wu, KY Chen, MH Wu, PJ Yang… - Biomedicine & …, 2022 - Elsevier
This study investigated the impacts of enteral cholecalciferol and/or intravenous calcitriol
administration on the balance of cluster of differentiation 4-positive T cell subsets, the renin …

DNA methylation and telomeres—Their impact on the occurrence of atrial fibrillation during cardiac aging

A Grzeczka, S Graczyk, P Kordowitzki - International Journal of Molecular …, 2023 - mdpi.com
Atrial fibrillation (AF) is the most common arrhythmia in humans. AF is characterized by
irregular and increased atrial muscle activation. This high-frequency activation obliterates …

[HTML][HTML] Mutation-driven parallel evolution in emergence of ACE2-utilizing sarbecoviruses

B Gao, S Zhu - Frontiers in Microbiology, 2023 - frontiersin.org
Mutation and recombination are two major genetic mechanisms that drive the evolution of
viruses. They both exert an interplay during virus evolution, in which mutations provide a first …

[HTML][HTML] Catch your breath: The protective role of the angiotensin AT2 receptor for the treatment of idiopathic pulmonary fibrosis

ON Young, JE Bourke, RE Widdop - Biochemical Pharmacology, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease whereby
excessive deposition of extracellular matrix proteins (ECM) ultimately leads to respiratory …

[HTML][HTML] The Role of ACE2 in Neurological Disorders: From Underlying Mechanisms to the Neurological Impact of COVID-19

J Li, X Kong, T Liu, M Xian… - International Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Angiotensin-converting enzyme 2 (ACE2) has become a hot topic in neuroscience research
in recent years, especially in the context of the global COVID-19 pandemic, where its role in …