Coagulopathy and haemorrhagic progression in traumatic brain injury: advances in mechanisms, diagnosis, and management

M Maegele, H Schöchl, T Menovsky… - The Lancet …, 2017 - thelancet.com
Normal haemostasis depends on an intricate balance between mechanisms of bleeding and
mechanisms of thrombosis, and this balance can be altered after traumatic brain injury (TBI) …

Management of moderate and severe traumatic brain injury

PA Abdelmalik, N Draghic, GSF Ling - Transfusion, 2019 - Wiley Online Library
Traumatic brain injury (TBI) is a common disorder with high morbidity and mortality,
accounting for one in every three deaths due to injury. Older adults are especially …

The European guideline on management of major bleeding and coagulopathy following trauma

DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

The European guideline on management of major bleeding and coagulopathy following trauma

R Rossaint, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2016 - Springer
Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Coagulopathy induced by traumatic brain injury: systemic manifestation of a localized injury

J Zhang, F Zhang, J Dong - Blood, The Journal of the American …, 2018 - ashpublications.org
Traumatic brain injury (TBI)–induced coagulopathy is a common and well-recognized risk for
poor clinical outcomes, but its pathogenesis remains poorly understood, and treatment …

Management of patients suffering from mild traumatic brain injury 2023

C Gil-Jardiné, JF Payen, R Bernard, X Bobbia… - … Critical Care & Pain …, 2023 - Elsevier
Objective To develop a multidisciplinary French reference that addresses initial pre-and in-
hospital management of a mild traumatic brain injury patient. Design A panel of 22 experts …

Diagnostic and therapeutic approach in adult patients with traumatic brain injury receiving oral anticoagulant therapy: an Austrian interdisciplinary consensus …

M Wiegele, H Schöchl, A Haushofer, M Ortler, J Leitgeb… - Critical care, 2019 - Springer
There is a high degree of uncertainty regarding optimum care of patients with potential or
known intake of oral anticoagulants and traumatic brain injury (TBI). Anticoagulation therapy …

Critical care management of traumatic brain injury

DK Menon, A Ercole - Handbook of clinical neurology, 2017 - Elsevier
Traumatic brain injury (TBI) is a growing global problem, which is responsible for a
substantial burden of disability and death, and which generates substantial healthcare costs …

Global characterisation of coagulopathy in isolated traumatic brain injury (iTBI): a CENTER-TBI analysis

JK Böhm, H Güting, S Thorn, N Schäfer, V Rambach… - Neurocritical care, 2021 - Springer
Background Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is
associated with high rates of complications, unfavourable outcomes and mortality. The …

Are antiplatelet and anticoagulants drugs a risk factor for bleeding in mild traumatic brain injury?

L Uccella, C Zoia, D Bongetta, P Gaetani, F Martig… - World neurosurgery, 2018 - Elsevier
Objective Facing mild traumatic brain injury, clinicians must decide whether to perform a
computed tomography (CT) scan to detect a potential intracranial hemorrhage. Many useful …