Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective
DL Pauls, A Abramovitch, SL Rauch… - Nature Reviews …, 2014 - nature.com
Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …
Mechanisms of glutamate transport
RJ Vandenberg, RM Ryan - Physiological reviews, 2013 - journals.physiology.org
l-Glutamate is the predominant excitatory neurotransmitter in the mammalian central
nervous system and plays important roles in a wide variety of brain functions, but it is also a …
nervous system and plays important roles in a wide variety of brain functions, but it is also a …
The error-related negativity (ERN/Ne)
We review two decades of research on the error-related negativity (ERN or Ne), a
component of the event-related brain potential that accompanies errors in speeded …
component of the event-related brain potential that accompanies errors in speeded …
Obsessive-compulsive disorder
Obsessive-compulsive disorder is a severe and disabling clinical condition that usually
arises in late adolescence or early adulthood and, if left untreated, has a chronic course …
arises in late adolescence or early adulthood and, if left untreated, has a chronic course …
Glutamate abnormalities in obsessive compulsive disorder: neurobiology, pathophysiology, and treatment
C Pittenger, MH Bloch, K Williams - Pharmacology & therapeutics, 2011 - Elsevier
Obsessive compulsive disorder is prevalent, disabling, incompletely understood, and often
resistant to current therapies. Established treatments consist of specialized cognitive …
resistant to current therapies. Established treatments consist of specialized cognitive …
Randomized controlled crossover trial of ketamine in obsessive-compulsive disorder: proof-of-concept
CI Rodriguez, LS Kegeles, A Levinson… - …, 2013 - nature.com
Serotonin reuptake inhibitors (SRIs), the first-line pharmacological treatment for obsessive-
compulsive disorder (OCD), have two limitations: incomplete symptom relief and 2–3 months …
compulsive disorder (OCD), have two limitations: incomplete symptom relief and 2–3 months …
Genome-wide association study of obsessive-compulsive disorder
Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative …
with complex genetic etiology. The International OCD Foundation Genetics Collaborative …
Biological markers for anxiety disorders, OCD and PTSD–a consensus statement. Part I: neuroimaging and genetics
B Bandelow, D Baldwin, M Abelli… - The World Journal of …, 2016 - Taylor & Francis
Objectives: Biomarkers are defined as anatomical, biochemical or physiological traits that
are specific to certain disorders or syndromes. The objective of this paper is to summarise …
are specific to certain disorders or syndromes. The objective of this paper is to summarise …
[图书][B] The noisy brain: stochastic dynamics as a principle of brain function
The activity of neurons in the brain is noisy in that their firing times are random when they
are firing at a given mean rate. This introduces a random or stochastic property into brain …
are firing at a given mean rate. This introduces a random or stochastic property into brain …
The genetics of obsessive-compulsive disorder: a review
DL Pauls - Dialogues in clinical neuroscience, 2010 - Taylor & Francis
Obsessive-compulsive disorder (OCD) is a serious psychiatric disorder that affects
approximately 2% of the populations of children and adults. Family aggregation studies …
approximately 2% of the populations of children and adults. Family aggregation studies …