MYC oncogene is a transcription factor with a wide array of functions affecting cellular
activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to …

Soon after the discovery of the Myc gene (c-Myc), it became clear that Myc expression levels
tightly correlate to cell proliferation. The entry in cell cycle of quiescent cells upon Myc …

Background: MicroRNAs (miRNAs) are involved in gastric cancer development and
progression. However, the expression and role of miRNAs in gastric cancer stromal cells are …

MicroRNAs (miRNAs) constitute a large class of short RNAs (eg, 20–24 nucleotides in
length), whose main function is to posttranscriptionally regulate the expression of protein …

Prostate cancer (PCa) is the most common type of cancer in men in the United States, which
disproportionately affects African American descents. While metastasis is the most common …

Gliomas are invasive brain tumors characterized by high rates of recurrence and mortality.
Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its …

Systematic physical activity increases physical fitness and exercise capacity that lead to the
improvement of health status and athletic performance. Considerable effort is devoted to …

DJ-1 is a highly conserved protein that protects neurons against oxidative stress and whose
loss of function mutations are linked to recessively inherited Parkinson's disease (PD). While …

Triple-negative breast cancer (TNBC), characterized by the lack of expression of the
estrogen receptor, the progesterone receptor, and the human epidermal growth factor …

Hyperglycemia is closely associated with prediabetes and Type 2 Diabetes Mellitus.
Hyperglycemia increases the risk of vascular complications such as diabetic retinopathy …