The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …

Neurofilament proteins (Nf) have been validated and established as a reliable body fluid
biomarker for neurodegenerative pathology. This review covers seven Nf isoforms, Nf light …

Previous studies indicate that FGF21 has ability to repair nerve injury, but the specific
mechanism is less studied. The present study was designed to investigate the effects of …

Objectives: To provide an objective characterization of acute neurologic injury in critically ill
patients with coronavirus disease 2019. Design: Prospective observational study …

Neurofilament light (NfL) is a scaffolding protein that is located primarily within myelinated
axons and that provides increased conduction speed and structural support. In recent years …

Coronary heart disease (CHD) is closely related to gut microbiota, which may be
significantly affected by ethnicity and the environment. Knowledge regarding the gut …

Background: Impaired cognition is a major predisposing factor for postoperative delirium, but
it is not systematically assessed. Anesthesia and surgery may cause postoperative delirium …

Background Stroke remains the most cumbersome disease burden in patients with cerebral
autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy …

Postoperative cognitive disorders after cardiac surgery may manifest as postoperative
delirium (POD) or later as postoperative cognitive dysfunction (POCD). The incidence of …

The ability to detect and analyze proteins, nucleic acids, and other biomolecules is critical for
clinical diagnostics and for understanding the underlying mechanisms of disease. Current …