Diagnosis and treatment of alcohol-associated liver disease: a review

AK Singal, P Mathurin - Jama, 2021 - jamanetwork.com
Importance Alcohol-associated liver disease results in cirrhosis in approximately 10% to
20% of patients. In 2017, more than 2 million people had alcohol-associated cirrhosis in the …

Impact of non-invasive biomarkers on hepatology practice: past, present and future

QM Anstee, L Castera, R Loomba - Journal of hepatology, 2022 - Elsevier
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …

EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update

A Berzigotti, E Tsochatzis, J Boursier, L Castera… - Journal of …, 2021 - Elsevier
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …

[HTML][HTML] Low accuracy of FIB-4 and NAFLD fibrosis scores for screening for liver fibrosis in the population

I Graupera, M Thiele, M Serra-Burriel… - Clinical …, 2022 - Elsevier
Background & Aims Fibrosis-4 (FIB-4) and the nonalcoholic fatty liver disease fibrosis score
(NFS) are the 2 most popular noninvasive blood-based serum tests proposed for …

[HTML][HTML] Limitations of non-invasive tests for assessment of liver fibrosis

K Patel, G Sebastiani - JHEP Reports, 2020 - Elsevier
The diagnostic assessment of liver injury is an important step in the management of patients
with chronic liver disease (CLD). Although liver biopsy is the reference standard for the …

Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting

MA Avila, JF Dufour, AL Gerbes, F Zoulim, R Bataller… - Gut, 2020 - gut.bmj.com
Alcohol-related liver disease (ALD), which includes a range of disorders of different severity
and is one of the most prevalent types of liver disease worldwide, has recently regained …

Noninvasive proteomic biomarkers for alcohol-related liver disease

L Niu, M Thiele, PE Geyer, DN Rasmussen… - Nature Medicine, 2022 - nature.com
Alcohol-related liver disease (ALD) is a major cause of liver-related death worldwide, yet
understanding of the three key pathological features of the disease—fibrosis, inflammation …

AASLD Practice Guideline on blood-based noninvasive liver disease assessment of hepatic fibrosis and steatosis

RK Sterling, K Patel, A Duarte-Rojo, SK Asrani… - Hepatology, 2025 - journals.lww.com
Chronic liver disease (CLD) leads to liver fibrosis; it is associated with approximately two
million annual deaths worldwide and is an enormous health burden.[1, 2] The majority of …

[HTML][HTML] Prognostic performance of 7 biomarkers compared to liver biopsy in early alcohol-related liver disease

DN Rasmussen, M Thiele, S Johansen… - Journal of …, 2021 - Elsevier
Background & aims Alcohol is the most common cause of liver-related mortality and
morbidity. We therefore aimed to assess and compare the prognostic performance of …

Alcohol-related liver disease: basic mechanisms and clinical perspectives

SY Liu, IT Tsai, YC Hsu - International journal of molecular sciences, 2021 - mdpi.com
Alcohol-related liver disease (ALD) refers to the liver damage occurring due to excessive
alcohol consumption and involves a broad spectrum of diseases that includes liver steatosis …