In recent years, tremendous progress has been made in understanding the roles of
extracellular vesicles (EVs) in cancer. Thanks to advancements in molecular biology, it has …

Neuronal activity drives alterations in gene expression within neurons, yet how it directs
transcriptional and epigenomic changes in neighboring astrocytes in functioning circuits is …

Bidirectional communication between tumours and neurons has emerged as a key facet of
the tumour microenvironment that drives malignancy,. Another hallmark feature of cancer is …

The hijacking of early developmental programs is a canonical feature of gliomas where
neoplastic cells resemble neurodevelopmental lineages and possess mechanisms of stem …

Pediatric intracranial ependymoma has seen a recent exponential expansion of biological
findings, rapidly dividing the diagnosis into several subgroups, each with specific molecular …

Brain metastasis poses formidable clinical challenges due to its intricate interactions with the
brain's unique immune environment, often resulting in poor prognoses. This review delves …

Background: Ependymomas are the third most common brain cancer in children and have
no targeted therapies. They are divided into at least 9 major subtypes based on molecular …

Astrocytes play key roles in brain function, but how these are orchestrated by transcription
factors (TFs) in the adult brain and aligned with astrocyte heterogeneity is largely unknown …

Background: Ependymomas are the third most common brain cancer in children and have
no targeted therapies. They are divided into at least 9 major subtypes based on molecular …

Temozolomide (TMZ) resistance is one of the major reasons for poor prognosis in patients
with glioblastoma (GBM). Long noncoding RNAs (lncRNAs) are involved in multiple …