The major transmembrane protein of the red blood cell, known as band 3, AE1, and
SLC4A1, has two main functions: 1) catalysis of Cl−/HC O 3− exchange, one of the steps in …

The hydrophobic lipid bitayer of the red cell membrane is nearly impermeable for hydrophilic
solutes. Nevertheless, the transport of CO2 in the blood involves a rapid exchange of HCO3 …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

Changes in cytosolic calcium concentrations regulate a wide variety of cellular processes,
and calcium-binding proteins are the key molecules in signal transduction, differentiation …

N‐Hydroxysulfosuccinimide esters are reactive functional groups employed in a variety of
protein modification reagents, especially cross‐linking reagents. For these compounds …

The electroneutral exchange of chloride and bicarbonate across the human erythrocyte
membrane is facilitated by Band 3, a 911 amino acid glycoprotein consisting of a 43 kDa N …

The bicarbonate/chloride exchanger band 3 (Anion Exchanger 1, AE1) is the most abundant
protein in the erythrocyte membrane, it has an important role in gas exchange and functions …

Conclusions Evidence from many laboratories using several different techniques strongly
suggests that, in the intact red cell, band 3 exists as dimers which can associate with other …

Activation of erbB-1 receptors by glial TGFα has been shown to be a component of the
developmental program by which the neuroendocrine brain controls mammalian sexual …

Synthetic cross-linking reagents, such as 3, 3′-dithiobis (sulfosuccinimidyl propionate),
DTSSP, can react with sidechains of amino acids that are within close proximity …