Heat shock proteins (HSPs) constitute a large family of proteins involved in protein folding
and maturation whose expression is induced by heat shock or other stressors. The major …

Abstract The 90-kiloDalton (kD) heat shock protein (Hsp90) is a ubiquitous, ATP-dependent
molecular chaperone whose primary function is to ensure the proper folding of several …

Background Genome-scale metabolic models (GEMs) offer insights into cancer metabolism
and have been used to identify potential biomarkers and drug targets. Drug repositioning is …

Survivin is an anti-apoptotic protein belonging to the inhibitor of apoptosis protein (IAP)
family. It is involved in the regulation of important physiological and pathological processes …

The identification of biomolecules associated with papillary thyroid cancer (PTC) has upmost
importance for the elucidation of the disease mechanism and the development of effective …

We and others propose vimentin as a possible cellular target for the treatment of COVID-19.
This innovative idea is so recent that it requires further attention and debate. The significant …

E-cadherin plays a pivotal role in cancer progression, including the epithelial-mesenchymal
transition (EMT) process and tumor metastasis. Loss of E-cadherin contributes to enhanced …

Simple Summary A promising approach to combat aggressive prostate cancer involves
androgen receptor degraders, which break down the crucial protein driving cancer …

Octamer‑binding transcription factor 4 (Oct4) has been identified as a novel transcription
factor associated with tumorigenesis, acquisition and maintenance of cancer stem cell …

Abstract Introduction: Heat shock proteins (HSPs) constitute a large family of proteins
involved in protein folding and maturation. HSP expression is induced by heat shock or …