Nongenomic actions of thyroid hormone
PJ Davis, F Goglia, JL Leonard - Nature Reviews Endocrinology, 2016 - nature.com
The nongenomic actions of thyroid hormone begin at receptors in the plasma membrane,
mitochondria or cytoplasm. These receptors can share structural homologies with nuclear …
mitochondria or cytoplasm. These receptors can share structural homologies with nuclear …
Molecular aspects of thyroid hormone actions
SY Cheng, JL Leonard, PJ Davis - Endocrine reviews, 2010 - academic.oup.com
Cellular actions of thyroid hormone may be initiated within the cell nucleus, at the plasma
membrane, in cytoplasm, and at the mitochondrion. Thyroid hormone nuclear receptors …
membrane, in cytoplasm, and at the mitochondrion. Thyroid hormone nuclear receptors …
Integrin αVβ3 Contains a Cell Surface Receptor Site for Thyroid Hormone that Is Linked to Activation of Mitogen-Activated Protein Kinase and Induction of …
JJ Bergh, HY Lin, L Lansing, SN Mohamed… - …, 2005 - academic.oup.com
Integrin αVβ3 is a heterodimeric plasma membrane protein whose several extracellular
matrix protein ligands contain an RGD recognition sequence. This study identifies integrin …
matrix protein ligands contain an RGD recognition sequence. This study identifies integrin …
Nongenomic steroid action: controversies, questions, and answers
RM Losel, E Falkenstein, M Feuring… - Physiological …, 2003 - journals.physiology.org
Lösel, Ralf M., Elisabeth Falkenstein, Martin Feuring, Armin Schultz, Hanns-Christian
Tillmann, Karin Rossol-Haseroth, and Martin Wehling. Nongenomic Steroid Action …
Tillmann, Karin Rossol-Haseroth, and Martin Wehling. Nongenomic Steroid Action …
Mechanisms of thyroid hormone receptor-specific nuclear and extra nuclear actions
JHD Bassett, CB Harvey, GR Williams - Molecular and cellular …, 2003 - Elsevier
Triiodothyronine (T3) classically regulates gene expression by binding to high-affinity thyroid
hormone receptors (TR) that recognize specific response elements in the promoters of T3 …
hormone receptors (TR) that recognize specific response elements in the promoters of T3 …
New insights into thyroid hormone action
A Oetting, PM Yen - Best practice & research Clinical endocrinology & …, 2007 - Elsevier
Thyroid hormones (THs) have important effects on cellular development, growth, and
metabolism. They bind to thyroid hormone receptors (TRs), TRα and TRβ, which belong to …
metabolism. They bind to thyroid hormone receptors (TRs), TRα and TRβ, which belong to …
l-Thyroxine vs. 3,5,3′-triiodo-l-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
HY Lin, M Sun, HY Tang, C Lin… - … of Physiology-Cell …, 2009 - journals.physiology.org
3, 5, 3′-Triiodo-l-thyronine (T3), but not l-thyroxine (T4), activated Src kinase and,
downstream, phosphatidylinositol 3-kinase (PI3-kinase) by means of an αvβ3 integrin …
downstream, phosphatidylinositol 3-kinase (PI3-kinase) by means of an αvβ3 integrin …
Membrane receptor for thyroid hormone: physiologic and pharmacologic implications
PJ Davis, FB Davis, SA Mousa… - Annual review of …, 2011 - annualreviews.org
Plasma membrane integrin αvβ3 is a cell surface receptor for thyroid hormone at which
nongenomic actions are initiated. L-thyroxine (T4) and 3, 3′, 5-triiodo-L-thyronine (T3) …
nongenomic actions are initiated. L-thyroxine (T4) and 3, 3′, 5-triiodo-L-thyronine (T3) …
Thyroid hormone causes mitogen-activated protein kinase-dependent phosphorylation of the nuclear estrogen receptor
HY Tang, HY Lin, S Zhang, FB Davis, PJ Davis - Endocrinology, 2004 - academic.oup.com
Activated by thyroid hormone, the MAPK (ERK1/2) signaling pathway causes serine
phosphorylation by MAPK of several nucleoproteins, including the nuclear thyroid hormone …
phosphorylation by MAPK of several nucleoproteins, including the nuclear thyroid hormone …
Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK-and p53-dependent mechanism
A Shih, FB Davis, HY Lin… - The Journal of Clinical …, 2002 - academic.oup.com
Two papillary thyroid carcinoma (PTC) and two follicular thyroid carcinoma (FTC) cell lines
treated with resveratrol (RV), 1–10 μm, showed activation and nuclear translocation of …
treated with resveratrol (RV), 1–10 μm, showed activation and nuclear translocation of …