Adverse food reactions include immune-mediated food allergies and non-immune-mediated
intolerances. However, this distinction and the involvement of different pathogenetic …

Helper T (Th) cell subsets direct immune responses by producing signature cytokines. Th2
cells produce IL-4, IL-5, and IL-13, which are important in humoral immunity and protection …

Background: The diagnosis of pediatric-onset inflammatory bowel disease (PIBD) can be
challenging in choosing the most informative diagnostic tests and correctly classifying PIBD …

Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …

Non–IgE-mediated gastrointestinal food-induced allergic disorders (non-IgE-GI-FAs)
account for an unknown proportion of food allergies and include food protein–induced …

Food allergies can result in life-threatening reactions and diminish quality of life. In the last
several decades, the prevalence of food allergies has increased in several regions …

Adverse immune responses to foods affect approximately 5% of young children and 3% to
4% of adults in westernized countries and appear to have increased in prevalence. Food …

Eosinophils have been considered end-stage cells involved in host protection against
parasites. However, numerous lines of evidence have now changed this perspective by …

Eosinophils have long been known to infiltrate tumors, and in most cases, this is associated
with an improved prognosis. However, the reasons behind this infiltration and the …

Tremendous progress has been made in our understanding of food-based allergic disorders
over the past 5 years. Recent epidemiologic studies suggest that nearly 4% of Americans …