[HTML][HTML] Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review

B Sun, L Wu, Y Wu, C Zhang, L Qin… - Frontiers in …, 2020 - frontiersin.org
Centella asiatica (also known as Centella asiatica (L.) Urb. or Gotu kola) is a traditional
Chinese medicine with extensive medicinal value, which is commonly used in Southeast …

[HTML][HTML] The Role of Ca2+-NFATc1 Signaling and Its Modulation on Osteoclastogenesis

JY Kang, N Kang, YM Yang, JH Hong… - International journal of …, 2020 - mdpi.com
The increasing of intracellular calcium concentration is a fundamental process for mediating
osteoclastogenesis, which is involved in osteoclastic bone resorption. Cytosolic calcium …

[HTML][HTML] A review on the molecular mechanisms of action of natural products in preventing bone diseases

IU Okagu, TPC Ezeorba, RN Aguchem… - International Journal of …, 2022 - mdpi.com
The drugs used for treating bone diseases (BDs), at present, elicit hazardous side effects
that include certain types of cancers and strokes, hence the ongoing quest for the discovery …

[HTML][HTML] Tetracyclic and pentacyclic triterpenes with high therapeutic efficiency in wound healing approaches

R Ghiulai, OJ Roşca, DS Antal, M Mioc, A Mioc… - Molecules, 2020 - mdpi.com
Wounds are among the most common skin conditions, displaying a large etiological diversity
and being characterized by different degrees of severity. Wound healing is a complex …

[HTML][HTML] Asiaticoside produces an antidepressant‑like effect in a chronic unpredictable mild stress model of depression in mice, involving reversion of inflammation …

L Wang, T Guo, Y Guo, Y Xu - Molecular Medicine …, 2020 - spandidos-publications.com
Asiaticoside is one of the triterpenoid components found in Centella asiatica that has
promising neuroprotective properties. The present study aimed to evaluate the …

Ethnobotany, Phytochemistry and Pharmacological Features of Centella asiatica: A Comprehensive Review

FA Torbati, M Ramezani, R Dehghan, MS Amiri… - … Properties of Plant …, 2021 - Springer
Centella asiatica (CA) or Gotu cola is an herbal plant from the Apiaceae family with a long
history of usage in different traditional medicines. It has long been used for the treatment of …

Oleanane- and Ursane-Type Triterpene Saponins from Centella asiatica Exhibit Neuroprotective Effects

ZW Wu, WB Li, J Zhou, X Liu, L Wang… - Journal of Agricultural …, 2020 - ACS Publications
Six new pentacyclic triterpenoid saponins, centelloside F (1), centelloside G (2), 11-oxo-
asiaticoside B (3), 11-oxo-madecassoside (4), 11 (β)-methoxy asiaticoside B (5), and 11 (β) …

[HTML][HTML] Functional materials of 3D bioprinting for wound dressings and skin tissue engineering applications: A review

H Fang, J Xu, H Ma, J Liu, E Xing… - … Journal of Bioprinting, 2023 - ncbi.nlm.nih.gov
The skin plays an important role in vitamin D synthesis, humoral balance, temperature
regulation, and waste excretion. Due to the complexity of the skin, fluids loss, bacterial …

Asiaticoside reverses M2 phenotype macrophage polarization-evoked osteosarcoma cell malignant behaviour by TRAF6/NF-κB inhibition

D Li, G Wang - Pharmaceutical Biology, 2022 - Taylor & Francis
Context M2 phenotype macrophage polarization is an attractive target for therapeutic
intervention. Asiaticoside (ATS) has multiple pharmacological functions. Objective This study …

[HTML][HTML] Asiaticoside suppresses cell proliferation by inhibiting the NF‑κB signaling pathway in colorectal cancer

X Zhou, C Ke, Y Lv, C Ren, T Lin… - International …, 2020 - spandidos-publications.com
Colorectal cancer (CRC) is one of the leading causes of cancer‑associated mortality.
Asiaticoside (AC) exhibits antitumor effects; however, to the best of our knowledge, the …