Small-molecule pheromones and hormones controlling nematode development

RA Butcher - Nature chemical biology, 2017 - nature.com
The existence of small-molecule signals that influence development in Caenorhabditis
elegans has been known for several decades, but only in recent years have the chemical …

Caenorhabditis elegans (C. elegans) sample preparation for metabolomics and lipidomics analysis–A review

AL Santoro, PH Vendramini, DL Braga… - TrAC Trends in …, 2023 - Elsevier
Caenorhabditis elegans (C. elegans) is a powerful model organism which has been
extensively characterized at the genetic and cellular levels and used to study various …

Metabolomics reveals the perturbations in the metabolome of Caenorhabditis elegans exposed to titanium dioxide nanoparticles

C Ratnasekhar, M Sonane, A Satish… - Nanotoxicology, 2015 - Taylor & Francis
The increasing use of nanotechnology in our daily life can have many unintended effects
and pose adverse impact on human health, environment and ecosystems. Wider application …

Metabolomic “Dark Matter” Dependent on Peroxisomal β-Oxidation in Caenorhabditis elegans

AB Artyukhin, YK Zhang, AE Akagi… - Journal of the …, 2018 - ACS Publications
Peroxisomal β-oxidation (pβo) is a highly conserved fat metabolism pathway involved in the
biosynthesis of diverse signaling molecules in animals and plants. In Caenorhabditis …

Modular assembly of primary metabolic building blocks: a chemical language in C. elegans

FC Schroeder - Chemistry & biology, 2015 - cell.com
The metabolome of the nematode Caenorhabditis elegans, like that of other model
organisms, remained largely uncharacterized until recent studies demonstrated the …

Antioxidation and anti-aging activities of astaxanthin geometrical isomers and molecular mechanism involved in Caenorhabditis elegans

X Liu, X Chen, H Liu, Y Cao - Journal of functional foods, 2018 - Elsevier
Astaxanthin (AST) exists trans/cis forms in food. Currently, the functional activities and
molecular mechanisms of the geometrical isomers remain unclear. In this study, the anti …

Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans

AB Artyukhin, JJ Yim, J Srinivasan, Y Izrayelit… - Journal of Biological …, 2013 - ASBMB
The ascarosides, small-molecule signals derived from combinatorial assembly of primary
metabolism-derived building blocks, play a central role in Caenorhabditis elegans biology …

Reducing Mass Confusion over the Microbiome

A McAtamney, C Heaney, I Lizama-Chamu… - Analytical …, 2023 - ACS Publications
As genetic tools continue to emerge and mature, more information is revealed about the
identity and diversity of microbial community members. Genetic tools can also be used to …

Ascaroside pheromones: chemical biology and pleiotropic neuronal functions

JY Park, HJ Joo, S Park, YK Paik - International journal of molecular …, 2019 - mdpi.com
Pheromones are neuronal signals that stimulate conspecific individuals to react to
environmental stressors or stimuli. Research on the ascaroside (ascr) pheromones in …

Biosynthesis of Modular Ascarosides in C. elegans

O Panda, AE Akagi, AB Artyukhin… - Angewandte …, 2017 - Wiley Online Library
The nematode Caenorhabditis elegans uses simple building blocks from primary
metabolism and a strategy of modular assembly to build a great diversity of signaling …