Naturally and synthetically obtained lipophilic α-amino acids exhibit diverse properties and
applications in academia and industry. Unnatural hydrophobic/lipophilic amino acids lacking …

A simple and rapid access to fluorinated dithioesters was developed by a one-pot sequence
corresponding to a Grignard reaction—Mitsunobu type substitution. These activated …

Thioamides are widely used structures in pharmaceuticals and agrochemicals, as well as
important synthons for the construction of sulfur‐containing heterocycles. This report …

Abstract The synthesis of 1, 1-difluoro-1-alkenes was achieved by the treatment of
dithioesters and thioketones with trimethylsilyl 2-fluorosulfonyl-2, 2-difluoroacetate in the …

A synthetic method has been developed for the preparation of dihalo (pyridinium) sulfuranes
and their transformation into alkynylthiopyridinium salts, starting from inexpensive …

One of the most fundamental concepts of organic chemistry is the classification of organic
molecules or fragments thereof into electrophiles (Greek:“electron loving”) and nucleophiles …

ANOTACE: Ústředním motivem této disertační práce je využití α-bromovaných laktamů coby
nových substrátů pro provedení Eschenmoserovy reakce (ECR). Při reakcích s primárními a …