Organ‐on‐a‐chip platforms seek to recapitulate the complex microenvironment of human
organs using miniaturized microfluidic devices. Besides modeling healthy organs, these …

Chronic lung diseases represent a largely global burden whose pathogenesis remains
largely unknown. Research increasingly suggests that epigenetic modifications, especially …

Rationale The blood is a rich source of potential biomarkers for the diagnosis of idiopathic
and hereditary pulmonary arterial hypertension (iPAH and hPAH, referred to as “PAH”) …

Ring finger 213 (RNF213) is a susceptibility gene for moyamoya disease (MMD), a
progressive cerebrovascular disease. Recent studies suggest that RNF213 plays an …

Pre-capillary pulmonary arterial hypertension (PAH) is hemodynamically characterized by a
mean pulmonary arterial pressure (mPAP)≥ 20 mmHg, pulmonary capillary wedge …

Heart failure (HF) is the end result of many different cardiac and non-cardiac abnormalities
leading to a complex clinical entity. In this view, the use of biomarkers in HF should be …

Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains,
contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1–4, EHD2 …

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive parenchymal scarring,
leading to dyspnoea, respiratory failure and premature death. Although IPF is confined to the …

Introduction: Flask-shaped plasma membrane (PM) invaginations called caveolae and their
constitutive caveolin and cavin proteins regulate cellular function via plasma membrane and …

Abstract The imbalance of Th17/Treg cells plays an important role in the pathogenesis of
chronic obstructive pulmonary disease (COPD). Caveolin-1 (Cav-1) has been regarded as a …