Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease

D Margină, A Ungurianu, C Purdel… - Food and chemical …, 2020 - Elsevier
Prevention and treatment of non-communicable diseases (NCDs), including cardiovascular
disease, diabetes, obesity, cancer, Alzheimer's and Parkinson's disease, arthritis, non …

Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?

V Cristina Oliveira de Lima, G Piuvezam… - Journal of enzyme …, 2019 - Taylor & Francis
The increase in non-communicable chronic diseases has aroused interest in the research of
adjuvants to the classic forms of treatments. Obesity and metabolic syndrome are the main …

Tamarind trypsin inhibitor in chitosan–whey protein nanoparticles reduces fasting blood glucose levels without compromising insulinemia: A preclinical study

LLR Matias, ROA Costa, TS Passos, JLC Queiroz… - Nutrients, 2019 - mdpi.com
In vivo studies show the benefits of the trypsin inhibitor isolated from tamarind
(Tamarindusindica L.)(TTI) seeds in satiety and obesity. In the present study, TTI …

An Insulin Receptor-Binding Multifunctional Protein from Tamarindus indica L. Presents a Hypoglycemic Effect in a Diet-Induced Type 2 Diabetes—Preclinical Study

I Costa, M Lima, A Medeiros, L Bezerra, P Santos… - Foods, 2022 - mdpi.com
The objectives of this study were to evaluate the hypoglycemic effect of the trypsin inhibitor
isolated from tamarind seeds (TTI) in an experimental model of T2DM and the in silico …

Nanoparticles Loaded with a Carotenoid-Rich Extract from Cantaloupe Melon Improved Hepatic Retinol Levels in a Diet-Induced Obesity Preclinical Model

C de Carvalho Gomes, MSR Lima, GLR de Oliveira… - ACS …, 2023 - ACS Publications
The study evaluated the effect of the carotenoid-rich extract from cantaloupe melon (CE)
nanoencapsulated in porcine gelatin (EPG) on hepatic retinol concentration and liver …

Anti-TNF-α Agent Tamarind Kunitz Trypsin Inhibitor Improves Lipid Profile of Wistar Rats Presenting Dyslipidemia and Diet-induced Obesity Regardless of PPAR-γ …

FMC Carvalho, VCO Lima, IS Costa, ABS Luz… - Nutrients, 2019 - mdpi.com
The increasing prevalence of obesity and, consequently, chronic inflammation and its
complications has increased the search for new treatment methods. The effect of the purified …

Potentially obesogenic diets alter metabolic and neurobehavioural parameters in Wistar rats: A comparison between two dietary models

THF do Bonfim, RL Tavares… - Journal of Affective …, 2021 - Elsevier
Background Clinical studies related to the obesity pandemic have intensified in recent years,
being the animal studies are also considered of great relevance. However, despite the fact …

Obesity influences the development of bisphosphonate-induced osteonecrosis in Wistar rats

WJM Lima, JCX PONTES, LS FIGUEIREDO… - Journal of Applied Oral …, 2023 - SciELO Brasil
Medication-related osteonecrosis of the jaw (MRONJ) is characterized by bone exposure for
more than eight weeks in patients who have used or been treated with antiresorptive or …

[HTML][HTML] Safety and potential functionality of nanoparticles loaded with a trypsin inhibitor isolated from tamarind seeds

RO de Araújo Costa, LLR Matias, TS Passos… - Future Foods, 2020 - Elsevier
The trypsin inhibitor isolated from tamarind seeds (TTI) presents satietogenic and anti-
inflammatory effects. In the present study, TTI encapsulation by nanoprecipitation in purified …

Beneficial effects of tamarind trypsin inhibitor in chitosan–whey protein nanoparticles on hepatic injury induced high glycemic index diet: a preclinical study

AJFC Aguiar, JLC de Queiroz, PPA Santos… - International Journal of …, 2021 - mdpi.com
Several studies have sought new therapies for obesity and liver diseases. This study
investigated the effect of the trypsin inhibitor isolated from tamarind seeds (TTI) …