Pulmonary fibrosis and architectural remodeling of tissues can severely disrupt lung
function, often with fatal consequences. The etiology of pulmonary fibrotic diseases is varied …

The role of inflammation in idiopathic pulmonary fibrosis (IPF) is controversial. If
inflammation were critical to the disease process, lung pathology would demonstrate an …

Objective. Biomarkers of progression of interstitial lung disease (ILD) are needed to allow
early therapeutic intervention in patients with scleroderma-associated disease (SSc-ILD) …

The CXC chemokine family is a pleiotropic family of cytokines that are involved in promoting
the trafficking of various leukocytes, in regulating angiogenesis and vascular remodeling …

Idiopathic pulmonary fibrosis (IPF) is a disabling disease of the lung parenchyma,
characterized by progressive accumulation of scar tissue and myofibroblast activation after …

Rationale: The implication of T cells in the pathogenesis of idiopathic pulmonary fibrosis
(IPF) is controversial. CD4+ CD25+ FOXP3+ regulatory T cells (Tregs) are pivotal in …

Introduction: Sarcoidosis is a complex systemic disease with a silent, long-term evolution,
and a heterogeneous clinical presentation. The diagnostic approach is complex with no …

Structural cell migration plays a central role in the pathophysiology of several diseases,
including asthma. Previously, we established that IL-17–induced (CXCL1, CXCL2, and …

Background: We conducted two independent nested case-control studies to identify
circulating inflammation markers reproducibly associated with lung cancer risk and to …

Chronic inflammatory pulmonary diseases are characterized by recurrent and persistent
inflammation of the airways, commonly associated with poor clinical outcomes. Although …