Introduction Selective androgen receptor modulators (SARMs) differentially bind to
androgen receptors depending on each SARM's chemical structure. As a result, SARMs …

Nuclear receptors are ligand-activated transcription factors and include the receptors for
steroid hormones, lipophilic vitamins, sterols, and bile acids. These receptors serve as …

Selective androgen receptor modulators (SARMs) are small molecule drugs that function as
either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins …

Interest in the development and therapeutic potential of nonsteroidal tissue-selective
androgen receptor modulators (SARMs) a has increased dramatically within the past …

Testosterone derivatives and related compounds (such as anabolic-androgenic steroids—
AAS) are frequently misused by athletes (both professional and amateur) wishing to promote …

The class of selective androgen receptor modulators (SARMs) has been the subject of
intense and dedicated clinical research over the past two decades. Potential therapeutic …

Anabolic androgenic steroids (AAS) are testosterone and testosterone-derivative
compounds sporadically employed by athletes and increasingly used recreationally to …

In our effort to find small-molecule treatments of advanced prostate cancers (PCs), a novel
series of indolyl and indolinyl propanamides (series II and III) were discovered as selective …

Use of testosterone replacement therapy (TRT) and anabolic–androgenic steroids (AAS)
has increased over the last 20 years, coinciding with an increase in men presenting with …

Gender confirmation surgery is increasingly common in persons with gender dysphoria. We
describe changes seen in gonads from individuals seeking male-to-female physical …