Nuclear magnetic resonance spectroscopy in clinical metabolomics and personalized medicine: current challenges and perspectives
MPM Letertre, P Giraudeau, P De Tullio - Frontiers in Molecular …, 2021 - frontiersin.org
Personalized medicine is probably the most promising area being developed in modern
medicine. This approach attempts to optimize the therapies and the patient care based on …
medicine. This approach attempts to optimize the therapies and the patient care based on …
Biomarkers of hypoxic–ischemic encephalopathy: a systematic review
I Caramelo, M Coelho, M Rosado… - World Journal of …, 2023 - Springer
Background Current diagnostic criteria for hypoxic–ischemic encephalopathy in the early
hours lack objective measurement tools. Therefore, this systematic review aims to identify …
hours lack objective measurement tools. Therefore, this systematic review aims to identify …
How could metabolomics change pediatric health?
F Bardanzellu, V Fanos - Italian Journal of Pediatrics, 2020 - Springer
In the last years,'omics' technologies, and especially metabolomics, emerged as expanding
scientific disciplines and promising technologies in the characterization of several …
scientific disciplines and promising technologies in the characterization of several …
Exploring perinatal asphyxia by metabolomics
Brain damage related to perinatal asphyxia is the second cause of neuro-disability
worldwide. Its incidence was estimated in 2010 as 8.5 cases per 1000 live births worldwide …
worldwide. Its incidence was estimated in 2010 as 8.5 cases per 1000 live births worldwide …
Thiamine as a possible neuroprotective strategy in neonatal hypoxic-ischemic encephalopathy
GP Sechi, F Bardanzellu, MC Pintus, MM Sechi… - Antioxidants, 2021 - mdpi.com
On the basis that similar biochemical and histological sequences of events occur in the brain
during thiamine deficiency and hypoxia/ischemia related brain damage, we have planned …
during thiamine deficiency and hypoxia/ischemia related brain damage, we have planned …
Urinary metabotypes of newborns with perinatal asphyxia undergoing therapeutic hypothermia
E Valerio, V Mardegan, M Stocchero, ME Cavicchiolo… - Plos one, 2022 - journals.plos.org
Perinatal asphyxia (PA) still occurs in about three to five per 1,000 deliveries in developed
countries; 20% of these infants show hypoxic-ischemic encephalopathy (HIE) on brain …
countries; 20% of these infants show hypoxic-ischemic encephalopathy (HIE) on brain …
Metabolomics investigation of post-mortem human pericardial fluid
A Chighine, M Stocchero, G Ferino… - International Journal of …, 2023 - Springer
Introduction Due to its peculiar anatomy and physiology, the pericardial fluid is a biological
matrix of particular interest in the forensic field. Despite this, the available literature has …
matrix of particular interest in the forensic field. Despite this, the available literature has …
Metabolomics improves the histopathological diagnosis of asphyxial deaths: an animal proof-of-concept model
The diagnosis of mechanical asphyxia remains one of the most difficult issues in forensic
pathology. Asphyxia ultimately results in cardiac arrest (CA) and, as there are no specific …
pathology. Asphyxia ultimately results in cardiac arrest (CA) and, as there are no specific …
A metabolomic approach in search of neurobiomarkers of perinatal asphyxia: a review of the current literature
MJ Debuf, K Carkeek, F Piersigilli - Frontiers in pediatrics, 2021 - frontiersin.org
Perinatal asphyxia and the possible sequelae of hypoxic-ischemic encephalopathy (HIE),
are associated with high morbidity and mortality rates. The use of therapeutic hypothermia …
are associated with high morbidity and mortality rates. The use of therapeutic hypothermia …
The Urinary Metabolome of Newborns with Perinatal Complications
Maternal pathological conditions such as infections and chronic diseases, along with
unexpected events during labor, can lead to life-threatening perinatal outcomes. These …
unexpected events during labor, can lead to life-threatening perinatal outcomes. These …