Recent developments in antimalarial activities of 4-aminoquinoline derivatives
Malaria is the fifth most lethal parasitic infection in the world. Antimalarial medications have
played a crucial role in preventing and eradicating malaria. Numerous heterocyclic moieties …
played a crucial role in preventing and eradicating malaria. Numerous heterocyclic moieties …
Recent developments in biological aspects of chalcones: the odyssey continues
Introduction: Chalcones are attractive to synthetic chemists because they are easy to
prepare, have a large number of replaceable hydrogens, thereby having significant …
prepare, have a large number of replaceable hydrogens, thereby having significant …
An in silico-in vitro antimalarial and antimicrobial investigation of newer 7-chloroquinoline based Schiff-bases
Abstract New fifteen 7-chloroquinolines (M1a-o) were synthesized by microwave irradiation
and conventional route via Schiff-base reaction. The key intermediate 4-((7-chloroquinolin-4 …
and conventional route via Schiff-base reaction. The key intermediate 4-((7-chloroquinolin-4 …
The application of microwaves, ultrasounds, and their combination in the synthesis of nitrogen-containing bicyclic heterocycles
F Frecentese, F Sodano, A Corvino… - International journal of …, 2023 - mdpi.com
The use of alternative energy sources, such as microwaves (MW) or ultrasounds (US), and
their mutual cross-combination have been widely described in the literature in the …
their mutual cross-combination have been widely described in the literature in the …
Recent developments in the synthesis of hybrid antimalarial drug discovery
BP Raiguru, J Panda, S Mohapatra, S Nayak - Bioorganic Chemistry, 2023 - Elsevier
In this 21 st century, Malaria remains a global burden and causes massive economic trouble
to disease-endemic nations. The control and eradication of malaria is a major challenge that …
to disease-endemic nations. The control and eradication of malaria is a major challenge that …
Current pharmaceutical aspects of synthetic quinoline derivatives
Quinoline derivatives are considered broad-spectrum pharmacological compounds that
exhibit a wide range of biological activities. Integration of quinoline moiety can improve its …
exhibit a wide range of biological activities. Integration of quinoline moiety can improve its …
1H-1,2,3-Triazole Tethered Nitroimidazole–Isatin Conjugates: Synthesis, Docking, and Anti-Proliferative Evaluation against Breast Cancer
1 H-1, 2, 3-Triazole tethered imidazole–isatin and imidazole–isatin–thiosemicarbazone
conjugates were synthesized and evaluated against MCF-7 and MDA-MB-231 cell lines …
conjugates were synthesized and evaluated against MCF-7 and MDA-MB-231 cell lines …
Synthesis, anti-plasmodial and cytotoxic evaluation of 1H-1, 2, 3-triazole/acyl hydrazide integrated tetrahydro-β-carboline-4-aminoquinoline conjugates
B Sharma, S Kaur, J Legac, PJ Rosenthal… - Bioorganic & Medicinal …, 2020 - Elsevier
Abstract A series of 1H-1, 2, 3-triazole/acylhydrazide-tethered tetrahydro-β-carboline-4-
aminoquinoline conjugates was synthesized with an aim to study their anti-plasmodial …
aminoquinoline conjugates was synthesized with an aim to study their anti-plasmodial …
Synthesis and antiplasmodial evaluation of 1H-1, 2, 3-triazole grafted 4-aminoquinoline-benzoxaborole hybrids and benzoxaborole analogues
Abstract A library of 1H-1, 2, 3-triazole-tethered 4-aminoquinoline-benzoxaborole hybrids as
well as aryl substituted benzoxaborole analogues was synthesized and screened for their …
well as aryl substituted benzoxaborole analogues was synthesized and screened for their …
Recent contributions of quinolines to antimalarial and anticancer drug discovery research
T Van de Walle, L Cools, S Mangelinckx… - European Journal of …, 2021 - Elsevier
Quinoline, a privileged scaffold in medicinal chemistry, has always been associated with a
multitude of biological activities. Especially in antimalarial and anticancer research …
multitude of biological activities. Especially in antimalarial and anticancer research …