[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Calreticulin in phagocytosis and cancer: opposite roles in immune response outcomes

A Schcolnik-Cabrera, B Oldak, M Juárez… - Apoptosis, 2019 - Springer
Calreticulin (CRT) is a pleiotropic and highly conserved molecule that is mainly localized in
the endoplasmic reticulum. Recently, CRT has gained special interest for its functions …

New strategies for evaluating imidacloprid-induced biological consequences targeted to Eisenia fetida species and the corresponding mechanisms of its toxicity

F He, J Wan, C Huo, X Li, Z Cui, Y Li, R Liu… - Journal of Environmental …, 2024 - Elsevier
Imidacloprid (IMI), a neonicotinoid insecticide, has a wide variety of applications in both
agriculture and horticulture. As a result of it massive and repeated use, its traces remained in …

[HTML][HTML] Immunogenic cell death and its therapeutic or prognostic potential in high-grade glioma

B Decraene, Y Yang, F De Smet, AD Garg… - Genes & …, 2022 - nature.com
Immunogenic cell death (ICD) has emerged as a key component of therapy-induced anti-
tumor immunity. Over the past few years, ICD was found to play a pivotal role in a wide …

Determination of calreticulin using Fe3O4@ AuNPs core-shell functionalized with PT (COOH) 2 polymer modified electrode: a new platform for the impedimetric …

EB Aydın, M Aydın, MK Sezgintürk - Sensors and Actuators B: Chemical, 2022 - Elsevier
An innovative biosensing design strategy was utilized for the first time to develop a label-free
and practical immunosensor for ultrasensitive analysis of calreticulin (CRT), a potential …

[HTML][HTML] Immunostimulatory properties of chemotherapy in breast cancer: From immunogenic modulation mechanisms to clinical practice

J Zhang, S Pan, C Jian, L Hao, J Dong, Q Sun… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) is the most common malignancy among females. Chemotherapy drugs
remain the cornerstone of treatment of BC and undergo significant shifts over the past 100 …

[HTML][HTML] Proteomics-based identification of dysregulated proteins in breast cancer

AN Neagu, M Jayathirtha, D Whitham, P Mutsengi… - Proteomes, 2022 - mdpi.com
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …

Impedimetric detection of calreticulin by a disposable immunosensor modified with a single-walled carbon nanotube-conducting polymer nanocomposite

EB Aydın, M Aydın, MK Sezgintürk - ACS Biomaterials Science & …, 2022 - ACS Publications
A label-free impedimetric immunosensing system was constructed for ultrasensitive
determination of the calreticulin (CALR) biological marker in human serum samples utilizing …

Mechanistic insights into pyridine exposure induced toxicity in model Eisenia fetida species: Evidence from whole-animal, cellular, and molecular-based perspectives

F He, T Qi, S Guo, H Wang, Z Zhang, R Liu, W Zong - Chemosphere, 2023 - Elsevier
Pyridine and its derivatives are widely used in many applications and inevitably cause
extreme scenarios of serious soil contamination, which pose a threat to soil organisms. Still …

Calreticulin as a marker and therapeutic target for cancer

M Zhang, J Xiao, J Liu, X Bai, X Zeng, Z Zhang… - Clinical and Experimental …, 2023 - Springer
Calreticulin (CRT) is a multifunctional protein found within the endoplasmic reticulum (ER).
In addition, CRT participates in the formation and development of tumors and promotes the …