Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

[HTML][HTML] Current and novel polymeric biomaterials for neural tissue engineering

R Boni, A Ali, A Shavandi, AN Clarkson - Journal of biomedical science, 2018 - Springer
The nervous system is a crucial component of the body and damages to this system, either
by of injury or disease, can result in serious or potentially lethal consequences. Restoring …

Traumatic spinal cord injury—repair and regeneration

CS Ahuja, S Nori, L Tetreault, J Wilson, B Kwon… - …, 2017 - journals.lww.com
BACKGROUND: Traumatic spinal cord injuries (SCI) have devastating consequences for the
physical, financial, and psychosocial well-being of patients and their caregivers. Expediently …

Concise review: bridging the gap: novel neuroregenerative and neuroprotective strategies in spinal cord injury

CS Ahuja, M Fehlings - Stem cells translational medicine, 2016 - academic.oup.com
Spinal cord injuries (SCIs) result in devastating lifelong disability for patients and their
families. The initial mechanical trauma is followed by a damaging secondary injury cascade …

[HTML][HTML] Neural tissue engineering with structured hydrogels in CNS models and therapies

J George, CC Hsu, LTB Nguyen, H Ye, Z Cui - Biotechnology advances, 2020 - Elsevier
The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …

Hydrogels and cell based therapies in spinal cord injury regeneration

RC Assunção-Silva, ED Gomes, N Sousa… - Stem cells …, 2015 - Wiley Online Library
Spinal cord injury (SCI) is a central nervous system‐(CNS‐) related disorder for which there
is yet no successful treatment. Within the past several years, cell‐based therapies have …

[HTML][HTML] Recent advances in managing a spinal cord injury secondary to trauma

CS Ahuja, AR Martin, M Fehlings - F1000Research, 2016 - ncbi.nlm.nih.gov
Traumatic spinal cord injuries (SCIs) affect 1.3 million North Americans, producing
devastating physical, social, and vocational impairment. Pathophysiologically, the initial …

[HTML][HTML] Hydrogels in spinal cord injury repair: A review

Z Lv, C Dong, T Zhang, S Zhang - Frontiers in bioengineering and …, 2022 - frontiersin.org
Traffic accidents and falling objects are responsible for most spinal cord injuries (SCIs). SCI
is characterized by high disability and tends to occur among the young, seriously affecting …

Recent advances in nanotherapeutic strategies for spinal cord injury repair

YH Song, NK Agrawal, JM Griffin, CE Schmidt - Advanced drug delivery …, 2019 - Elsevier
Spinal cord injury (SCI) is a devastating and complicated condition with no cure available.
The initial mechanical trauma is followed by a secondary injury characterized by …

Cell-seeded alginate hydrogel scaffolds promote directed linear axonal regeneration in the injured rat spinal cord

MI Günther, N Weidner, R Müller, A Blesch - Acta Biomaterialia, 2015 - Elsevier
Despite recent progress in enhancing axonal growth in the injured spinal cord, the guidance
of regenerating axons across an extended lesion site remains a major challenge. To …