Coordinating radiometals of copper, gallium, indium, yttrium, and zirconium for PET and SPECT imaging of disease

TJ Wadas, EH Wong, GR Weisman… - Chemical …, 2010 - ACS Publications
Molecular imaging is the visualization, characterization, and measurement of biological
processes at the molecular and cellular levels in humans and other living systems …

[HTML][HTML] Development of copper based drugs, radiopharmaceuticals and medical materials

P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

Starch capped atomically thin CuS nanocrystals for efficient photothermal therapy

Z Zheng, P Yu, H Cao, M Cheng, T Zhou, LE Lee… - Small, 2021 - Wiley Online Library
Photothermal therapy requires efficient plasmonic nanomaterials with small size, good water
dispersibility, and biocompatibility. This work reports a one‐pot, 2‐min synthesis strategy for …

A practical guide to the construction of radiometallated bioconjugates for positron emission tomography

BM Zeglis, JS Lewis - Dalton Transactions, 2011 - pubs.rsc.org
Positron emission tomography (PET) has become a vital imaging modality in the diagnosis
and treatment of disease, most notably cancer. A wide array of small molecule PET …

Bombesin related peptides/receptors and their promising therapeutic roles in cancer imaging, targeting and treatment

P Moreno, I Ramos-Álvarez, TW Moody… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Despite remarkable advances in tumor treatment, many patients still die from
common tumors (breast, prostate, lung, CNS, colon, and pancreas), and thus, new …

Bombesin receptor-mediated imaging and cytotoxicity: review and current status

V Sancho, A Di Florio, TW Moody… - Current drug …, 2011 - ingentaconnect.com
The three mammalian bombesin (Bn) receptors (gastrin-releasing peptide [GRP] receptor,
neuromedin B [NMB] receptor, BRS-3) are one of the classes of G protein-coupled receptors …

Radiometallated peptides for molecular imaging and targeted therapy

JDG Correia, A Paulo, PD Raposinho, I Santos - Dalton Transactions, 2011 - pubs.rsc.org
In developed countries, cancer is the second leading cause of death, being only surpassed
by cardiovascular diseases. To develop tumor-targeted tools to localize and treat cancer at …

Imaging cancer using PET—the effect of the bifunctional chelator on the biodistribution of a 64Cu-labeled antibody

JLJ Dearling, SD Voss, P Dunning, E Snay… - Nuclear medicine and …, 2011 - Elsevier
INTRODUCTION: Use of copper radioisotopes in antibody radiolabeling is challenged by
reported loss of the radionuclide from the bifunctional chelator used to label the protein. The …

Multimodal tumor-targeting peptides functionalized with both a radio-and a fluorescent label

J Kuil, AH Velders, FWB van Leeuwen - Bioconjugate chemistry, 2010 - ACS Publications
The use of monolabeled tumor-targeting peptides for molecular imaging is widespread.
However, it is often desirable to use the same compound for different clinical applications …

[HTML][HTML] Radiolabelled peptides for oncological diagnosis

P Laverman, JK Sosabowski, OC Boerman… - European journal of …, 2012 - Springer
Radiolabelled receptor-binding peptides targeting receptors (over) expressed on tumour
cells are widely under investigation for tumour diagnosis and therapy. The concept of using …