Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects
KP Smith, KM Gifford, JS Waitzman, SE Rice - Biophysical Journal, 2015 - cell.com
While it is currently estimated that 40-50% of eukaryotic proteins are phosphorylated, little is
known about the frequency and local effects of phosphorylation near pharmaceutical …
known about the frequency and local effects of phosphorylation near pharmaceutical …
Clinical trials of mitotic kinesin inhibitors
SS Rosenfeld - Kinesins and Cancer, 2015 - Springer
Abnormal mitotic activity underlies the pathology of a number of human diseases, most
notably cancer, and has motivated the search for more specific and less toxic inhibitors of …
notably cancer, and has motivated the search for more specific and less toxic inhibitors of …