Aptamers as a replacement for antibodies in enzyme-linked immunosorbent assay

SY Toh, M Citartan, SCB Gopinath, TH Tang - Biosensors and …, 2015 - Elsevier
The application of antibodies in enzyme-linked immunosorbent assay (ELISA) is the basis of
this diagnostic technique which is designed to detect a potpourri of complex target …

[HTML][HTML] Oligonucleotide aptamers for pathogen detection and infectious disease control

Q Wan, X Liu, Y Zu - Theranostics, 2021 - ncbi.nlm.nih.gov
During an epidemic or pandemic, the primary task is to rapidly develop precise diagnostic
approaches and effective therapeutics. Oligonucleotide aptamer-based pathogen detection …

Graphene functionalized field-effect transistors for ultrasensitive detection of Japanese encephalitis and Avian influenza virus

A Roberts, N Chauhan, S Islam, S Mahari, B Ghawri… - Scientific Reports, 2020 - nature.com
Graphene, a two-dimensional nanomaterial, has gained immense interest in biosensing
applications due to its large surface-to-volume ratio, and excellent electrical properties …

A versatile biomimic nanotemplating fluidic assay for multiplex quantitative monitoring of viral respiratory infections and immune responses in saliva and blood

R Siavash Moakhar, C del Real Mata… - Advanced …, 2022 - Wiley Online Library
The last pandemic exposed critical gaps in monitoring and mitigating the spread of viral
respiratory infections at the point‐of‐need. A cost‐effective multiplexed fluidic device …

Strategies using bio-layer interferometry biosensor technology for vaccine research and development

RL Petersen - Biosensors, 2017 - mdpi.com
Bio-layer interferometry (BLI) real-time, label-free technology has greatly contributed to
advances in vaccine research and development. BLI Octet platforms offer high-throughput …

[HTML][HTML] Predicting the uncertain future of aptamer-based diagnostics and therapeutics

JG Bruno - Molecules, 2015 - mdpi.com
Despite the great promise of nucleic acid aptamers in the areas of diagnostics and
therapeutics for their facile in vitro development, lack of immunogenicity and other desirable …

Dual recognition element lateral flow assay toward multiplex strain specific influenza virus detection

TT Le, P Chang, DJ Benton, JW McCauley… - Analytical …, 2017 - ACS Publications
Different influenza virus strains have caused a number of recent outbreaks killing scores of
people and causing significant losses in animal farming. Simple, rapid, sensitive, and …

Subtyping of influenza A H1N1 virus using a label-free electrochemical biosensor based on the DNA aptamer targeting the stem region of HA protein

J Bhardwaj, N Chaudhary, H Kim, J Jang - Analytica chimica acta, 2019 - Elsevier
Rapid subtyping of influenza viruses in clinical laboratories has been increasingly important
because three subtypes (seasonal H1N1, H3N2, and 2009 H1N1) of influenza A virus …

Antivirals targeting the surface glycoproteins of influenza virus: Mechanisms of action and resistance

Y Bai, JC Jones, SS Wong, M Zanin - Viruses, 2021 - mdpi.com
Hemagglutinin and neuraminidase, which constitute the glycoprotein spikes expressed on
the surface of influenza A and B viruses, are the most exposed parts of the virus and play …

Aptamer-based diagnostic and therapeutic approaches for animal viruses: A review

Z Chen, Q Sun, Y Yang, X Nie, W Xiang, Y Ren… - International Journal of …, 2024 - Elsevier
Animal diseases often have significant consequences due to the unclear and time-
consuming diagnosis process. Furthermore, the emergence of new viral infections and drug …