Tumor cells actively produce, release, and utilize exosomes to promote tumor growth.
Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …

Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

Tumor-derived exosomes (TEX) are harbingers of tumor-induced immune suppression: they
carry immunosuppressive molecules and factors known to interfere with immune cell …

Interleukin-2 (IL-2) is a pleiotropic cytokine produced after antigen activation that plays
pivotal roles in the immune response. Discovered as a T cell growth factor, IL-2 additionally …

Summary Foxp3+ regulatory T (Treg) cells maintain immune homeostasis by limiting
different types of inflammatory responses. Here, we report that miR-146a, one of the miRNAs …

Toll-like receptor (TLR) signalling must be tightly regulated to avoid excessive inflammation
and to allow for tissue repair and the return to homeostasis after infection and tissue injury …

MicroRNAs (miRNAs or miRs) are a class of evolutionarily-conserved small, regulatory non-
coding RNAs, 19–3 nucleotides in length, that negatively regulate protein coding gene …

Abstract CD4+ T helper (TH) cells regulate appropriate cellular and humoral immune
responses to a wide range of pathogens and are central to the success of vaccines …

Abstract miRNAs are small non-coding RNA molecules that modulate the expression of
multiple protein-encoding genes at the post-transcriptional level. They have recently been …

The discovery of micro RNA s (miRNAs) in the early 1990's has revolutionized our thinking
of post‐transcriptional gene control. miRNAs are involved in the regulation of almost every …