An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

K Ziqubu, PV Dludla, SXH Mthembu… - Frontiers in …, 2023 - frontiersin.org
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy
expenditure, has been extensively studied as a potential avenue to combat obesity …

Adipose tissue adipokines and lipokines: Functions and regulatory mechanism in skeletal muscle development and homeostasis

X Gu, L Wang, S Liu, T Shan - Metabolism, 2023 - Elsevier
Skeletal muscle plays important roles in normal biological activities and whole-body energy
homeostasis in humans. The growth and development of skeletal muscle also directly …

Adipokines from white adipose tissue in regulation of whole body energy homeostasis

B Sahu, NC Bal - Biochimie, 2023 - Elsevier
Diseases originating from altered energy homeostasis including obesity, and type 2
diabetes are rapidly increasing worldwide. Research in the last few decades on animal …

Brown adipose tissue-derived metabolites and their role in regulating metabolism

K Ziqubu, PV Dludla, SE Mabhida, BU Jack, S Keipert… - Metabolism, 2024 - Elsevier
The discovery and rejuvenation of metabolically active brown adipose tissue (BAT) in adult
humans have offered a new approach to treat obesity and metabolic diseases. Beyond its …

Metabolism in type 2 immune responses

AM Kabat, EL Pearce, EJ Pearce - Immunity, 2023 - cell.com
The immune response is tailored to the environment in which it takes place. Immune cells
sense and adapt to changes in their surroundings, and it is now appreciated that in addition …

An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications

Z Ghesmati, M Rashid, S Fayezi, F Gieseler… - Reviews in Endocrine …, 2024 - Springer
Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and
beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT …

Interplay between the brain and adipose tissue: a metabolic conversation

F Díaz-Castro, E Morselli, M Claret - EMBO reports, 2024 - embopress.org
The central nervous system and adipose tissue interact through complex communication.
This bidirectional signaling regulates metabolic functions. The hypothalamus, a key …

Highly expandable edible hydrogels for the prevention and treatment of obesity through dietary intervention

H Yang, H Yang, C Zhu, D Fan, J Deng - Food Hydrocolloids, 2023 - Elsevier
Long treatment periods, high risk of operation, and large side effects of drugs are the main
factors, affecting obesity treatment. Obesity prevention or treatment through dietary …

Disease progression promotes changes in adipose tissue signatures in type 2 diabetic (db/db) mice: The potential pathophysiological role of batokines

K Ziqubu, PV Dludla, MT Moetlediwa, TA Nyawo… - Life Sciences, 2023 - Elsevier
Unlike the white adipose tissue (WAT) which mainly stores excess energy as fat, brown
adipose tissue (BAT) has become physiologically important and therapeutically relevant for …

Brown adipose tissue and novel management strategies for polycystic ovary syndrome therapy

Q Zhang, R Ye, YY Zhang, CC Fan, J Wang… - Frontiers in …, 2022 - frontiersin.org
Brown adipose tissue (BAT), a unique tissue, plays a key role in metabolism and energy
expenditure through adaptive nonshivering thermogenesis. It has recently become a …