Safety of antipsychotics for the treatment of schizophrenia: a focus on the adverse effects of clozapine

D De Berardis, G Rapini, L Olivieri… - … advances in drug …, 2018 - journals.sagepub.com
Clozapine, a dibenzodiazepine developed in 1961, is a multireceptorial atypical
antipsychotic approved for the treatment of resistant schizophrenia. Since its introduction, it …

Inflammation in venous thromboembolism: cause or consequence?

A Saghazadeh, S Hafizi, N Rezaei - International immunopharmacology, 2015 - Elsevier
Venous thromboembolism (VTE) which includes deep vein thrombosis (DVT) and
pulmonary thromboembolism (PTE) is a moderately common disease especially in elderly …

Dose-dependent effects of antipsychotics on efficacy and adverse effects in schizophrenia

K Yoshida, H Takeuchi - Behavioural Brain Research, 2021 - Elsevier
Background Antipsychotics are a cornerstone of pharmacological treatment of
schizophrenia. Improved understanding of the dose-response relationship of antipsychotics …

Use and safety of antipsychotics in behavioral disorders in elderly people with dementia

P Gareri, P De Fazio, VGL Manfredi… - Journal of clinical …, 2014 - journals.lww.com
In recent years, the use of antipsychotics has been widely debated for reasons concerning
their safety in elderly patients affected with dementia. To update the use of antipsychotics in …

Current antipsychotic agent use and risk of venous thromboembolism and pulmonary embolism: a systematic review and meta-analysis of observational studies

Y Liu, J Xu, K Fang, Y Xu, J Gao… - Therapeutic …, 2021 - journals.sagepub.com
Background: Antipsychotic agents (APS) are widely used drugs to treat psychotic symptoms
and can effectively reduce both positive and negative symptoms of schizophrenia. For …

Venous thromboembolism during treatment with antipsychotics: a review of current evidence

AK Jönsson, J Schill, H Olsson, O Spigset, S Hägg - CNS drugs, 2018 - Springer
This article summarises the current evidence on the risk of venous thromboembolism (VTE)
with the use of antipsychotics. An increasing number of observational studies indicate an …

[PDF][PDF] Psychotropic medications in older adults: a review

M Ćurković, K Dodig-Ćurković, A Petek Erić… - Psychiatria …, 2016 - hrcak.srce.hr
PSYCHOTROPIC MEDICATIONS IN OLDER ADULTS: A REVIEW Page 1 13 Psychiatria
Danubina, 2016; Vol. 28, No. 1, pp 13-24 Review © Medicinska naklada - Zagreb, Croatia …

Antipsychotic drug exposure and risk of venous thromboembolism: a systematic review and meta-analysis of observational studies

C Barbui, V Conti, A Cipriani - Drug safety, 2014 - Springer
Background Venous thromboembolism (VTE) is a serious disorder that may be complicated
by pulmonary embolism (PE). Case reports and observational studies published in the early …

Fatal pulmonary embolism in patients on antipsychotics: case series, systematic review and meta-analysis

SA Manoubi, M Boussaid, O Brahim, S Ouanes… - Asian Journal of …, 2022 - Elsevier
Since the 1950 s, several studies have reported that patients using first generation and/or
second-generation antipsychotics had increased risk of venous thromboembolism events …

Antipsychotic use and risk of venous thromboembolism: a meta-analysis

X Di, M Chen, S Shen, X Cui - Psychiatry Research, 2021 - Elsevier
Objective: This study aimed to evaluate the association between antipsychotic drugs (APs)
and the risk of venous thromboembolism (VTE). Methods: We searched Pubmed, Embase …