Human antimicrobial peptides and proteins

G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

[PDF][PDF] Saliva–the defender of the oral cavity

AVN Amerongen, ECI Veerman - Oral diseases, 2002 - Citeseer
It is generally accepted that saliva is of paramount importance for the maintenance of oral
health. This is based on the numerous studies reporting subjective and objective functional …

The chromogranin–secretogranin family

L Taupenot, KL Harper… - New England Journal of …, 2003 - Mass Medical Soc
The members of the chromogranin–secretogranin family of peptide hormones, biogenic
amines, and neurotransmitters are enclosed within vesicles in the neuroendocrine system …

Antimicrobial peptides: natural effectors of the innate immune system

K Radek, R Gallo - Seminars in immunopathology, 2007 - Springer
Antimicrobial peptides (AMPs) are an evolutionarily conserved component of the innate
immune system that defend against invading bacteria, viruses, and fungi through membrane …

Effects of exercise intensity on salivary antimicrobial proteins and markers of stress in active men

JE Allgrove, E Gomes, J Hough… - Journal of sports …, 2008 - Taylor & Francis
In the present study, we assessed the effects of exercise intensity on salivary
immunoglobulin A (s-IgA) and salivary lysozyme (s-Lys) and examined how these …

The insulin secretory granule as a signaling hub

J Suckale, M Solimena - Trends in Endocrinology & Metabolism, 2010 - cell.com
The insulin granule was previously thought of as merely a container, but accumulating
evidence suggests that it also acts as a signaling node. Regulatory pathways intersect at but …

The nervous system and innate immunity: the neuropeptide connection

KA Brogden, JM Guthmiller, M Salzet, M Zasloff - Nature immunology, 2005 - nature.com
Many neuropeptides and peptide hormones are very similar to antimicrobial peptides in their
amino acid composition, amphipathic design, cationic charge and size. Their antimicrobial …

The clinical relevance of chromogranin A as a biomarker for gastroenteropancreatic neuroendocrine tumors

B Lawrence, BI Gustafsson, M Kidd… - Endocrinology and …, 2011 - endo.theclinics.com
An accurate tumor marker is a critical tool in tumor management because it establishes an
uncertain diagnosis, offers a basis for individual prognostication, signals response to …

Potential roles of histones in host defense as antimicrobial agents

H Kawasaki, S Iwamuro - Infectious Disorders-Drug Targets …, 2008 - ingentaconnect.com
Antimicrobial peptides (AMPs), which are widely distributed in various organisms, comprise
part of the host innate defense system to kill or damage bacterial and fungal pathogens …

Antimicrobial activity associated with extracellular matrices

A Sarikaya, R Record, CC Wu, B Tullius… - Tissue …, 2002 - liebertpub.com
Materials derived from extracellular matrices (ECMs) are being evaluated as scaffolds for
surgical reconstruction of damaged or missing tissues. It is important to understand the …