Efficacy and safety of NSAIDs in infants: a comprehensive review of the literature of the past 20 years

VC Ziesenitz, T Welzel, M van Dyk, P Saur, M Gorenflo… - Pediatric Drugs, 2022 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in infants, children, and
adolescents worldwide; however, despite sufficient evidence of the beneficial effects of …

Current state of analgesia and sedation in the pediatric intensive care unit

C Egbuta, KP Mason - Journal of Clinical Medicine, 2021 - mdpi.com
Critically ill pediatric patients often require complex medical procedures as well as invasive
testing and monitoring which tend to be painful and anxiety-provoking, necessitating the …

A meta-analysis of the use of nonsteroidal antiinflammatory drugs for pediatric postoperative pain

D Michelet, J Andreu-Gallien, T Bensalah… - Anesthesia & …, 2012 - journals.lww.com
BACKGROUND: Opioid side effects are a great concern during the postoperative period in
children. Nonsteroidal antiinflammatory drugs (NSAIDs) have been shown to effectively …

Ketorolac for postoperative pain in children

ED McNicol, E Rowe… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Children who undergo surgical procedures in ambulatory and inpatient settings
are at risk of experiencing acute pain. Nonsteroidal anti‐inflammatory drugs (NSAIDs) can …

Perioperative care of infants with pyloric stenosis

M Kamata, RS Cartabuke, JD Tobias - Pediatric Anesthesia, 2015 - Wiley Online Library
Pyloric stenosis (PS) is one of the most common surgical conditions affecting neonates and
young infants. The definitive treatment for PS is surgical pyloromyotomy, either open or …

Clinical pharmacokinetic studies in pregnant women and the relevance of pharmacometric tools

A Dallmann, P Mian, JV den Anker… - Current …, 2019 - ingentaconnect.com
Background: In clinical pharmacokinetic (PK) studies, pregnant women are significantly
underrepresented because of ethical and legal reasons which lead to a paucity of …

Quantitative determination of taurine and related biomarkers in urine by liquid chromatography–tandem mass spectrometry

S Gamagedara, H Shi, Y Ma - Analytical and bioanalytical chemistry, 2012 - Springer
Current urinary bladder cancer diagnosis is commonly based on a biopsy obtained during
cystoscopy. This invasive method causes discomfort and pain in patients. Recently, taurine …

Pediatric pain management: a review

FT O'Donnell, KR Rosen - Missouri medicine, 2014 - pmc.ncbi.nlm.nih.gov
Although the occurrence of pain in hospitalized children is common, assessment and
treatment of pain presents unique challenges to practitioners who care for pediatric patients …

Off-label use of medications in children undergoing sedation and anesthesia

MC Smith, J Williamson, M Yaster… - Anesthesia & …, 2012 - journals.lww.com
BACKGROUND: Many drugs used for anesthesia and analgesia in children are
administered “off-label.” We undertook an audit of drugs commonly used for pediatric …

Nonopioid analgesics for perioperative and cardiac surgery pain in children: current evidence and knowledge gaps

A Saini, KO Maher, SR Deshpande - Annals of Pediatric …, 2020 - journals.lww.com
Objective: The purpose of this review is to present the available literature on the use of
nonopioid analgesics such as nonsteroidal anti-inflammatory drugs in postcardiac surgery …