Cellular-mediated inflammatory response, lymphocytes, neutrophils, and monocytes are
increasingly being recognised as having an important role in tumorigenesis and …

Background Operative injury to the body from all procedures causes a stereotypical cascade
of neuroendocrine, cytokine, myeloid, and acute phase responses. This response has been …

Surgery is an important treatment modality for the majority of solid organ cancers.
Unfortunately, cancer recurrence following surgery of curative intent is common, and …

Background The presence of a high neutrophil-to-lymphocyte ratio (NLR) has been
associated with increased mortality in several malignancies. Here, we quantify the effect of …

Aims This study aimed to evaluate the prognostic effect of neutrophil‐to‐lymphocyte ratio
(NLR) and platelet‐to‐lymphocyte ratio (PLR) for patients with breast cancer (BC). Methods …

Cimetidine, the first H 2 receptor antagonist in widespread clinical use, has anti-cancer
properties that have been elucidated in a broad range of pre-clinical and clinical studies for …

Platinum based drugs alone or in combination with 5FU and docetaxel are common regimen
chemotherapeutics for the treatment of advanced OSCC. Chemoresistance is one of the …

Inflammatory blood markers (IBM), such as the neutrophil to lymphocyte ratio (NLR), have
emerged as potential prognostic factors in various cancers, including breast cancer (BC) …

IMMUNE PATHOGENESIS The principal line of defense against cancer cell invasion and
metastasis is established via the host's innate and adaptive immune response. The key …

A pumpless, reconfigurable, multi-organ–on–a–chip system containing recirculating serum-
free medium can be used to predict preclinical on-target efficacy, metabolic conversion, and …