The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …

Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …

The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …

The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

In the field of nasal drug delivery, nose-to-brain delivery is among the most fascinating
applications, directly targeting the central nervous system, bypassing the blood brain barrier …

Although nanomedicine have greatly developed and human life span has been extended,
we have witnessed the soared incidence of central nervous system (CNS) diseases …

Restricted drug entry to the brain that is closely associated with the existence of the blood
brain barrier (BBB) has limited the accessibility of most potential active therapeutic …

Silica nanoparticles are widely used for biomedical purposes, but also in cosmetic products,
food, the car industry, paints, etc. Considering their mega production, one should not ignore …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive and
behavioral impairment. Curcumin-loaded mesoporous silica nanoparticles (MSN-CCM) can …