Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration

E Afshinnekoo, RT Scott, MJ MacKay, E Pariset… - Cell, 2020 - cell.com
Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …

Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars

ZS Patel, TJ Brunstetter, WJ Tarver, AM Whitmire… - npj …, 2020 - nature.com
NASA's plans for space exploration include a return to the Moon to stay—boots back on the
lunar surface with an orbital outpost. This station will be a launch point for voyages to …

Human health during space travel: state-of-the-art review

C Krittanawong, NK Singh, RA Scheuring, E Urquieta… - Cells, 2022 - mdpi.com
The field of human space travel is in the midst of a dramatic revolution. Upcoming missions
are looking to push the boundaries of space travel, with plans to travel for longer distances …

Factors mediating spaceflight-induced skeletal muscle atrophy

PHU Lee, M Chung, Z Ren… - American Journal of …, 2022 - journals.physiology.org
Skeletal muscle atrophy is a well-known consequence of spaceflight. Because of the
potential significant impact of muscle atrophy and muscle dysfunction on astronauts and …

Mechanical energy metamaterials in interstellar travel

P Jiao - Progress in Materials Science, 2023 - Elsevier
Nanoscale spacecrafts have shed light on an audacious but promising vision for interstellar
travel to neighboring planets beyond the solar system. The nanocrafts can be accelerated to …

Biological research and self-driving labs in deep space supported by artificial intelligence

LM Sanders, RT Scott, JH Yang, AA Qutub… - Nature Machine …, 2023 - nature.com
Abstract Space biology research aims to understand fundamental spaceflight effects on
organisms, develop foundational knowledge to support deep space exploration and …

Neuro-consequences of the spaceflight environment

SD Mhatre, J Iyer, S Puukila, AM Paul… - Neuroscience & …, 2022 - Elsevier
As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Towards sustainable human space exploration—priorities for radiation research to quantify and mitigate radiation risks

A Fogtman, S Baatout, B Baselet, T Berger… - npj …, 2023 - nature.com
Human spaceflight is entering a new era of sustainable human space exploration. By 2030
humans will regularly fly to the Moon's orbit, return to the Moon's surface and preparations …

A million persons, a million dreams: a vision for a national center of radiation epidemiology and biology

JD Boice, B Quinn, I Al-Nabulsi, A Ansari… - The Million Person …, 2024 - taylorfrancis.com
Background: Epidemiologic studies of radiation-exposed populations form the basis for
human safety standards. They also help shape public health policy and evidence-based …

Circulating miRNA spaceflight signature reveals targets for countermeasure development

S Malkani, CR Chin, E Cekanaviciute, M Mortreux… - Cell reports, 2020 - cell.com
We have identified and validated a spaceflight-associated microRNA (miRNA) signature that
is shared by rodents and humans in response to simulated, short-duration and long-duration …