Gene therapy: Comprehensive overview and therapeutic applications
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …
Next‐generation vaccines: nanoparticle‐mediated DNA and mRNA delivery
Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
[HTML][HTML] Emerging applications of nanotechnology in healthcare systems: Grand challenges and perspectives
Healthcare, as a basic human right, has often become the focus of the development of
innovative technologies. Technological progress has significantly contributed to the …
innovative technologies. Technological progress has significantly contributed to the …
[HTML][HTML] Adenovirus-mediated gene delivery: potential applications for gene and cell-based therapies in the new era of personalized medicine
CS Lee, ES Bishop, R Zhang, X Yu, EM Farina, S Yan… - Genes & diseases, 2017 - Elsevier
With rapid advances in understanding molecular pathogenesis of human diseases in the era
of genome sciences and systems biology, it is anticipated that increasing numbers of …
of genome sciences and systems biology, it is anticipated that increasing numbers of …
[HTML][HTML] Gene therapy: advances, challenges and perspectives
GAR Gonçalves, RMA Paiva - Einstein (Sao Paulo), 2017 - SciELO Brasil
The ability to make site-specific modifications to the human genome has been an objective
in medicine since the recognition of the gene as the basic unit of heredity. Thus, gene …
in medicine since the recognition of the gene as the basic unit of heredity. Thus, gene …
[HTML][HTML] Viral and nonviral delivery systems for gene delivery
N Nayerossadat, T Maedeh, PA Ali - Advanced biomedical …, 2012 - journals.lww.com
Gene therapy is the process of introducing foreign genomic materials into host cells to elicit
a therapeutic benefit. Although initially the main focus of gene therapy was on special …
a therapeutic benefit. Although initially the main focus of gene therapy was on special …
Gene therapy and DNA delivery systems
Gene therapy is a promising new technique for treating many serious incurable diseases,
such as cancer and genetic disorders. The main problem limiting the application of this …
such as cancer and genetic disorders. The main problem limiting the application of this …
[HTML][HTML] Applications of synthetic biology in medical and pharmaceutical fields
X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …
bioproperties. During the past decades, progresses have been made to build delicate …
Delivery and use of the CRISPR-Cas systems, vectors and compositions for hepatic targeting and therapy
F Zhang, L Cong, RAN Fei - US Patent 10,577,630, 2020 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
52105121&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
52105121&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Large-pore ultrasmall mesoporous organosilica nanoparticles: micelle/precursor co-templating assembly and nuclear-targeted gene delivery.
M Wu, Q Meng, Y Chen, Y Du, L Zhang… - … (Deerfield Beach, Fla.), 2014 - europepmc.org
A novel micelle/precursor co-templating assembly strategy is successfully developed to
synthesize large-pore ultrasmall mesoporous organosilica nanoparticles (MONs) …
synthesize large-pore ultrasmall mesoporous organosilica nanoparticles (MONs) …